ChemicalBook--->CAS DataBase List--->1259933-16-8

1259933-16-8

1259933-16-8 Structure

1259933-16-8 Structure
IdentificationBack Directory
[Name]

XEN402
[CAS]

1259933-16-8
[Synonyms]

XEN402
Funapide
TV-45070
XEN402;TV-45070
(7S)-1′-{[5-(trifluoromethyl)furan-2-yl]methyl}spiro[furo[2,3-f][1,3]benzodioxole-7,3′-indol]-2′(1′H)-one
(S)-1'-((5-(Trifluoromethyl)furan-2-yl)methyl)-6H-spiro[[1,3]dioxolo[4,5-f]benzofuran-7,3'-indolin]-2'-one
(3'S)-1'-[[5-(Trifluoromethyl)-2-furanyl]methyl]spiro[furo[2,3-f]-1,3-benzodioxole-7(6H),3'-[3H]indol]-2'(1'H)-one
Spiro[furo[2,3-f]-1,3-benzodioxole-7(6H),3'-[3H]indol]-2'(1'H)-one,1'-[[5-(trifluoromethyl)-2-furanyl]methyl]-,(3'S)-
[Molecular Formula]

C22H14F3NO5
[MDL Number]

MFCD28502435
[MOL File]

1259933-16-8.mol
[Molecular Weight]

429.35
Chemical PropertiesBack Directory
[Boiling point ]

612.2±55.0 °C(Predicted)
[density ]

1.59±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[form ]

Solid
[pka]

-0.53±0.20(Predicted)
[color ]

Off-white to light yellow
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
Hazard InformationBack Directory
[Uses]

Funapide is a small-molecule inhibitor of the sodium channel Nav1.7 and other sodium channels, including those that are expressed in the pain-sensing peripheral nervous system. It has potentially broad application in nociceptive pain, including inflammatory pain, and neuropathic pain indications.
[IC 50]

Nav1.7; Nav1.8
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