| Identification | Back Directory | [Name]
DHODH-IN-11 | [CAS]
1263303-95-2 | [Synonyms]
DHODH-IN-11
Acetamide, N-[1,1'-biphenyl]-4-yl-2-cyano-2-(hydroxyimino)-, (2E)- | [Molecular Formula]
C15H11N3O2 | [MOL File]
1263303-95-2.mol | [Molecular Weight]
265.27 |
| Chemical Properties | Back Directory | [density ]
1.21±0.1 g/cm3(Predicted) | [storage temp. ]
-20°C, protect from light | [solubility ]
DMSO: 125 mg/mL (471.22 mM) | [form ]
A solid | [pka]
7.63±0.10(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
DHODH-IN-11 (Compound 14b) is a Leflunomide derivative and a weak dihydroorotate dehydrogenase (DHODH) inhibitor with a pKa of 5.03[1]. | [References]
[1] Giorgis M, et al. 1,2,5-Oxadiazole analogues of leflunomide and related compounds. Eur J Med Chem. 2011 Jan;46(1):383-92. DOI:10.1016/j.ejmech.2010.10.029 |
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InvivoChem
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13549236410 |
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https://www.invivochem.cn/ |
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