| Identification | Back Directory | [Name]
ALA-LYS-PRO-GLU-ALA-PRO-GLY-GLU-ASP-ALA-SER-PRO-GLU-GLU-LEU-SER-ARG-TYR-TYR-ALA-SER-LEU-ARG-HIS-TYR-LEU-ASN-LEU-VAL-THR-ARG-GLN-ARG-TYR-NH2 | [CAS]
126339-09-1 | [Synonyms]
3-36-PeptideYY
Porcine peptide YY (3-36)
PEPTIDE YY (3-36), PORCINE
M.W. 3980.44 C176H272N52O54
peptide yy fragment 3-36 human
Peptide YY (3-36) (porcine, rat)
PEPTIDE YY (3-36), HUMAN, SYNTHETIC >97%
PYY (3-36) (canine, Mouse, porcine, rat)
Peptide YY FragMent 3-36 huManPeptide YY F
Peptide YY (3-36) (canine, mouse, porcine, rat)
Peptide YY Fragment 3-36 human >=95% (HPLC), lyophilized powder
ALA-LYS-PRO-GLU-ALA-PRO-GLY-GLU-ASP-ALA-SER-PRO-GLU-GLU-LEU-SER-ARG-TYR-TYR-ALA-SER-LEU-ARG-HIS-TYR-LEU-ASN-LEU-VAL-THR-ARG-GLN-ARG-TYR-NH2
REF DUPL: H-Ala-Lys-Pro-Glu-Ala-Pro-Gly-Glu-Asp-Ala-Ser-Pro-Glu-Glu-Leu-Ser-Arg-Tyr-Tyr-Ala-Ser-Leu-Arg-His-Tyr-Leu-Asn-Leu-Val-Thr-Arg-Gln-Arg-Tyr-NH2 | [Molecular Formula]
C176H272N52O54 | [MDL Number]
MFCD00286279 |
| Hazard Information | Back Directory | [Uses]
Peptide YY (PYY) (3-36), porcine is a gut hormone peptide that acts as a Y2 receptor agonist to reduce appetite. | [General Description]
Human peptide YY (PYY) is a 36 amino acid peptide secreted by mucosal L cells in the distal ileum, colon and rectum. The gene encoding PYY is localized on human chromosome 17q21.1. | [Biochem/physiol Actions]
Y2/Y5 Neuropeptide Y receptor agonist. Human peptide YY (PYY) has roles in energy homeostasis, food ingestion, gut motility and insulin secretion. The protein suppresses appetite. It has been associated with obesity and type 2 diabetes. | [in vivo]
In mice, actinonin significantly prolongs the anorectic effect of PYY3-36 (50 nmol/kg) and maintains higher PYY3-36 plasma levels than treatment with PYY3-36 alone[1]. | [storage]
Store at -20°C | [References]
[1] Addison ML, et al. A role for metalloendopeptidases in the breakdown of the gut hormone, PYY 3-36. Endocrinology. 2011 Dec;152(12):4630-40. DOI:10.1210/en.2011-1195 |
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