ChemicalBook--->CAS DataBase List--->127684-07-5

127684-07-5

127684-07-5 Structure

127684-07-5 Structure
IdentificationBack Directory
[Name]

5α,6beta-dihydroxycholestanol-d7
[CAS]

127684-07-5
[Synonyms]

Cholestanetriol-d7
5α,6-dihydroxycholestanol-d7
5α,6β-Dihydroxycholestanol-d7
5α,6ss-dihydroxycholestanol-d7
3β,5α,6β-Trihydroxycholestane-d7
[2H7]-3β,5α,6β-Trihydroxycholestane
(3S,5R,6R,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6,7,7,7-tetradeuterio-6-(trideuteriomethyl)heptan-2-yl]-1,2,3,4,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthrene-3,5,6-triol
[Molecular Formula]

C27H48O3
[MDL Number]

MFCD34568136
[MOL File]

127684-07-5.mol
[Molecular Weight]

420.68
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

Methanol: Slightly Soluble
[form ]

A solid
[InChIKey]

YMMFNKXZULYSOQ-UCHKBJBUSA-N
[SMILES]

[H][C@@]12[C@]([C@](CC[C@H](O)C3)(C)[C@@]3(O)[C@H](O)C2)([H])CC[C@@]4(C)[C@@]1([H])CC[C@]4([H])[C@]([H])(C)CCCC([2H])(C([2H])([2H])[2H])C([2H])([2H])[2H]
Safety DataBack Directory
[WGK Germany ]

WGK 3
[Storage Class]

11 - Combustible Solids
Hazard InformationBack Directory
[Uses]

Labelled Cholesterol analog. Useful for treatment of hyperlipemia, arteriosclerosis, diabetes, obesity.
[Biological Activity]

5α,6β-dihydroxycholestanol (5α,6β-diOH-Chol) or cholestane-3β,5α,6β-triol (C-triol) levels are elevated along with 7-ketocholesterol in Niemann-Pick type C (NP-C) disease and is a key biomarkers for detection. It has ,neuroprotective functionality and may elicit protection against neuronal injury during ischemia.
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