| Identification | Back Directory | [Name]
2-hydroxypropyl-α-cyclodextrin | [CAS]
128446-33-3 | [Synonyms]
HPACD
Cavasol? W6 HP
2-hydroxypropyl-α-cyclodextrin
Hydroxpropyl Alpha Cyclodextrim
(2-Hydroxyethyl)-a-cyclodextrin
(2-Hydroxypropyl)-a-cyclodextrin
HYDROXYPROPYL-ALPHA-CYCLODEXTRIN, MS=0.6
.alpha.-Cyclodextrin, 2-hydroxypropyl ethers
(2-Hydroxypropyl)-alpha-cyclodextrin average Mw ~1,180 | [EINECS(EC#)]
451-510-9 | [MDL Number]
MFCD00197866 |
| Chemical Properties | Back Directory | [Melting point ]
245 °C (dec.)(lit.) | [density ]
1.39 at 24.6℃ | [solubility ]
Soluble in water, methanol, DMF. Insoluble in acetone, chloroform. | [form ]
Solid powder | [color ]
White to off white | [Optical Rotation]
[α]20/D +125°, c = 1 in H2O | [Cosmetics Ingredients Functions]
FRAGRANCE
SKIN CONDITIONING | [InChIKey]
PMPYGZCSMCXHTA-WABPNHHRSA-N | [LogP]
-10.6--9.89 | [Surface tension]
66.1mN/m at 1g/L and 20℃ | [EPA Substance Registry System]
.alpha.-Cyclodextrin, 2-hydroxypropyl ethers (128446-33-3) |
| Hazard Information | Back Directory | [Uses]
- (2-Hydroxypropyl)-α-cyclodextrin can be used as a chiral selector to resolve tryptophan racemate by capillary electrophoresis.
- It can be used to synthesize biodegradable polyrotaxanes for fabricating blood-contacting devices.
- Co-polymer based on (2-hydroxypropyl)-α-cyclodextrin cross-linked with polyethylenimine can be used as a gene delivery vector.
- It can also be used as stabilizer for antibacterial iodine formulations, as it forms a stable inclusion complex with iodine and improves aqueous solubility.
| [General Description]
(2-Hydroxypropyl)-α-cyclodextrin is a hydroxyalkyl derivative of cyclodextrin, which is generally used as a substitute of α-cyclodextrin for potential application in food, cosmetics and pharmaceutical industries. It may be used as a parenteral drug carrier on account of its attractive characteristics such as: a greater extent of solubility in water, high dissolution capacity for weakly soluble analytes, and low toxicity. |
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| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
| Company Name: |
Cool Pharm, Ltd
|
| Telephone: |
021-60455363 18019463053 |
| Website: |
www.coolpharm.com |
| Company Name: |
Sigma-Aldrich
|
| Telephone: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
| Company Name: |
Rhawn Reagent
|
| Telephone: |
400-400-1332688 18019345275 |
| Website: |
http://www.rhawn.cn |
| Company Name: |
Cool Pharm, Ltd
|
| Telephone: |
021-58581007 18019463053 |
| Website: |
http://www.coolpharm.com.cn |
|