| Identification | Back Directory | [Name]
THP-PEG5 | [CAS]
128660-97-9 | [Synonyms]
THP-PEG5
THP-PEG4-OH
OH-PEG4-THP
CAS_128660-97-9
THP-PEG4-alcohol
Ethanol, 2-[2-[2-[2-[(tetrahydro-2H-pyran-2-yl)oxy]ethoxy]ethoxy]ethoxy]-
2-(2-(2-(2-((Tetrahydro-2H-pyran-2-yl)oxy)ethoxy)ethoxy)ethoxy)ethan-1-ol | [Molecular Formula]
C13H26O6 | [MDL Number]
MFCD26127805 | [MOL File]
128660-97-9.mol | [Molecular Weight]
278.34 |
| Hazard Information | Back Directory | [Description]
THP-PEG5 is a PEG linker containing a THP protecting group and a terminal hydroxyl group. THP is an acid labile, alcohol protecting group. The terminal hydroxyl group can undergo reactions to further derivatize the compound. The hydrophilic PEG linkers increase the water solubility properties of the compound in aqueous media. | [Uses]
THP-PEG4-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. DOI:10.1016/j.ebiom.2018.09.005 |
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| Company Name: |
Henan Alfachem Co.,Ltd.
|
| Telephone: |
0371-55051623 18137891487 |
| Website: |
www.chemicalbook.com/supplier/14555231/ |
| Company Name: |
Wuhan Topule
|
| Telephone: |
+86-02787215551 19945035818 |
| Website: |
http://www.topule.com/ |
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