| Identification | Back Directory | [Name]
3-(4-BROMOPHENYL)PYRIDINE | [CAS]
129013-83-8 | [Synonyms]
3-(4-BROMOPHENYL)PYRIDINE
Pyridine, 3-(4-bromophenyl)-
3-(4-Bromophenyl)pyridine >
3-(4-BROMOPHENYL)PYRIDINE ISO 9001：2015 REACH | [EINECS(EC#)]
807-991-6 | [Molecular Formula]
C11H8BrN | [MDL Number]
MFCD04116232 | [MOL File]
129013-83-8.mol | [Molecular Weight]
234.09 |
| Chemical Properties | Back Directory | [Melting point ]
38.0 to 42.0 °C | [Boiling point ]
331.9±17.0 °C(Predicted) | [density ]
1.426±0.06 g/cm3(Predicted) | [storage temp. ]
0-10°C | [form ]
powder to lump to clear liquid | [pka]
4.70±0.10(Predicted) | [color ]
White or Colorless to Light yellow | [InChI]
InChI=1S/C11H8BrN/c12-11-5-3-9(4-6-11)10-2-1-7-13-8-10/h1-8H | [InChIKey]
FCHUOBPHXDXZBK-UHFFFAOYSA-N | [SMILES]
C1=NC=CC=C1C1=CC=C(Br)C=C1 |
| Hazard Information | Back Directory | [Chemical Properties]
Pale yellow liquid | [Synthesis]
In a three-necked flask, p-bromoiodobenzene (28 g, 0.1 mol), pyridine-3-boronic acid (12.3 g, 0.1 mol), potassium carbonate (27.2 g, 200 mmol), tetrakis(triphenylphosphine)palladium (0.8 g), tetrahydrofuran (200 ml) and water (50 ml) were added. The reaction mixture was heated to reflux for 5 hours under nitrogen protection. After completion of the reaction, it was cooled to room temperature and filtered to remove insoluble material. The filtrate was purified by column chromatography to give 13 g of 3-(4-bromophenyl)pyridine in 56% yield. | [References]
[1] Patent: CN105753849, 2016, A. Location in patent: Paragraph 0056; 0057
[2] Chemistry - A European Journal, 2017, vol. 23, # 60, p. 15089 - 15097
[3] Patent: EP2065378, 2009, A1. Location in patent: Page/Page column 141 |
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