ChemicalBook--->CAS DataBase List--->129112-17-0

129112-17-0

129112-17-0 Structure

129112-17-0 Structure
IdentificationBack Directory
[Name]

EGFRvIII peptide (PEPvIII)
[CAS]

129112-17-0
[Synonyms]

EGFRvIII peptide (PEPvIII)
[Molecular Formula]

C70H111N19O24S
[MDL Number]

MFCD32068011
[MOL File]

129112-17-0.mol
[Molecular Weight]

1634.83
Chemical PropertiesBack Directory
[Boiling point ]

2021.1±65.0 °C(Predicted)
[density ]

1.348±0.06 g/cm3(Predicted)
[pka]

2.83±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

EGFRvIII peptide (PEPvIII) is a tumor-specific mutation that is widely expressed in glioblastoma multiforme (GBM) and other neoplasms and its expression enhances tumorigenicity. EGFRvIII peptide represents a truly tumor-specific target for antitumor immunotherapy[1].
[References]

[1] Schmittling RJ, et al. Detection of humoral response in patients with glioblastoma receiving EGFRvIII-KLH vaccines. J Immunol Methods. 2008 Nov 30;339(1):74-81. DOI:10.1016/j.jim.2008.08.004
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