| Identification | Back Directory | [Name]
(-)-CATECHIN GALLATE | [CAS]
130405-40-2 | [Synonyms]
(-)-CG
ECSMSZS
BCatechin gallate
()-Catechin gallat
(-)-CATECHIN GALLATE
(?)-Catechin Gallate
(-)-Catechin 3-gallate
CATECHIN GALLATE, (-)-
(-)-Catechin gallate(CG)
(-)-Catechin 3-O-gallate)
()-Catechin gallate, >=98%
Choriogonadotropin subunit β
(-)-Catechin gallate
(-)-CG
Chorionic gonadotrophin chain β
ANTI-CG antibody produced in mouse
Catechin gallate/(-)-Catechin gallate
Catechin gallate CG (-)-Catechin gallate
(-)-Catechin gallate, 98%, from Green tea
(-)-Catechin gallate ((-)-Catechin 3-gallate
Anti-HCG β, C-Terminal antibody produced in rabbit
(2S,3R)-2-(3,4-Dihydroxyphenyl)-5,7-dihydroxychroMan-3-yl 3,4,5-trihydroxybenzoate
(2S,3R)-2-(3,4-Dihydroxyphenyl)-3-(3,4,5-trihydroxybenzoyloxy)-3,4-dihydro-2H-1-benzopyran-5,7-diol
(2S,3R)-2-(3,4-DIHYDROXYPHENYL)-3,4-DIHYDRO-1(2H)-BENZOPYRAN-3,5,7-TRIOL 3-(3,4,5-TRIHYDROXYBENZOATE)
3,4,5-Trihydroxybenzoic Acid (2S,3R)-2-(3,4-Dihydroxyphenyl)-3,4-dihydro-5,7-dihydroxy-2H-1-benzopyran-3-yl Ester
3,4,5-Trihydroxybenzoic acid [[(2S)-2β-(3,4-dihydroxyphenyl)-3,4-dihydro-5,7-dihydroxy-2H-1-benzopyran]-3α-yl] ester
Benzoic acid, 3,4,5-trihydroxy-, (2S,3R)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-5,7-dihydroxy-2H-1-benzopyran-3-yl ester
()-Catechin gallate,(2S,3R)-2-(3,4-Dihydroxyphenyl)-3,4-dihydro-1(2H)-benzopyran-3,5,7-triol 3-(3,4,5-trihydroxybenzoate) | [Molecular Formula]
C22H18O10 | [MDL Number]
MFCD00214258 | [MOL File]
130405-40-2.mol | [Molecular Weight]
442.37 |
| Chemical Properties | Back Directory | [Melting point ]
248-251 °C (decomp) | [Boiling point ]
861.7±65.0 °C(Predicted) | [density ]
1.80±0.1 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
DMSO (Slightly), Ethanol (Slightly) | [form ]
Solid | [pka]
7.75±0.25(Predicted) | [color ]
Pale Yellow to Light Red | [biological source]
green tea | [Major Application]
metabolomics
vitamins, nutraceuticals, and natural products | [InChI]
1S/C22H18O10/c23-11-6-14(25)12-8-19(32-22(30)10-4-16(27)20(29)17(28)5-10)21(31-18(12)7-11)9-1-2-13(24)15(26)3-9/h1-7,19,21,23-29H,8H2/t19-,21+/m1/s1 | [InChIKey]
LSHVYAFMTMFKBA-CTNGQTDRSA-N | [SMILES]
Oc1cc(O)c2C[C@@H](OC(=O)c3cc(O)c(O)c(O)c3)[C@@H](Oc2c1)c4ccc(O)c(O)c4 | [LogP]
2.670 (est) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
36/37/38 | [Safety Statements ]
26-36 | [WGK Germany ]
3 | [HS Code ]
29329990 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| Hazard Information | Back Directory | [Chemical Properties]
White powder, soluble in organic solvents such as methanol, ethanol, DMSO, etc., derived from green tea. | [Uses]
A major component of green tea, is a dual phosphoinositide-3-kinase/mTOR inhibitor. | [Definition]
ChEBI: (-)-catechin-3-O-gallate is a gallate ester obtained by formal condensation of the carboxy group of gallic acid with the (3R)-hydroxy group of (-)-catechin. It has a role as a metabolite. It is a gallate ester, a polyphenol and a member of flavans. It is functionally related to a (-)-catechin and a gallic acid. It is an enantiomer of a (+)-catechin-3-O-gallate. | [General Description]
(?)-Catechin gallate belongs to a class of polyphenol compounds that are formed when catechins in green tea undergo epimerization on heat treatment. It is a naturally occurring flavanol catechin having a galloyl moiety. | [Biochem/physiol Actions]
Antioxidant constituent of green tea. At μM concentrations, it inhibits VEGF-induced tyrosine phosphorylation. It also inhibits aromatase activity, an enzyme that converts androgens to estrogen and is thought to play a role in the etiology of breast cancer. |
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