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130804-35-2

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130804-35-2 Structure

130804-35-2 Structure
IdentificationBack Directory
[Name]

lecimibide
[CAS]

130804-35-2
[Synonyms]

DuP 128
lecimibide
1-[5-(4,5-DIPHENYLIMIDAZOL-2-YLTHIO)PENTYL]-1-HEPTYL-3-(2,4-DIFLUOROPHENYL)UREA
Urea, N'-(2,4-difluorophenyl)-N-[5-[(4,5-diphenyl-1H-imidazol-2-yl)thio]pentyl]-N-heptyl-
3-(2,4-difluorophenyl)-1-[5-[(4,5-diphenyl-1H-imidazol-2-yl)sulfanyl]pentyl]-1-heptylurea
[Molecular Formula]

C34H40F2N4OS
[MDL Number]

MFCD00865717
[MOL File]

130804-35-2.mol
[Molecular Weight]

590.77
Hazard InformationBack Directory
[Uses]

Antihyperlipidemic.
[in vivo]

Lecimibide (DuP 128) (i.v., 2.2 mg/kg/day) significantly reduces total plasma triglyceride and very low-density lipoprotein (VLDL) triglyceride concentrations in pigs fed high fat and cholesterol levels, respectively 36% and 31%. There are no significant effects on total cholesterol, VLDL cholesterol, LDL cholesterol, HDL cholesterol, or LDL apoB concentrations[2].

Spectrum DetailBack Directory
[Spectrum Detail]

lecimibide(130804-35-2)1HNMR
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