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131096-89-4

131096-89-4 Structure

131096-89-4 Structure
IdentificationBack Directory
[Name]

CHOLERA TOXIN B SUBUNIT
[CAS]

131096-89-4
[Synonyms]

CTxB
abs80001
CHOLERA TOXIN B SUBUNIT
Cholera Toxin B subunit-FITC
Cholera toxin subunit B(CTB)
Cholera Toxin B Subunit (CTB)
VIBRIO CHOLERAE TOXIN B SUBUNIT
cholera toxin B subunit from*vibrio cholerae
CHOLERA TOXIN B SUBUNIT (LOW SALT) FORMU LATION OF CHOLER
CHOLERA TOXIN, B SUBUNIT, VIBRIO CHOLERAE, TYPE INABA 569B
CHOLERA TOXIN B SUBUNIT VIBRIO CHOLERAE, PEROXIDASE CONJUGATE
[MDL Number]

MFCD00130778
Chemical PropertiesBack Directory
[storage temp. ]

-20°C
[solubility ]

H2O: 10 mg/mL, soluble
[form ]

solid
[color ]

white
[Water Solubility ]

H2O: soluble 11mg/mL
[Specific Activity]

(Binds to GM1 ganglioside. The binding EC50 is lower than 1 ug/ml)
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H312+H332-H412
[Precautionary statements ]

P261-P271-P273-P280-P302+P352+P312-P304+P340+P312
[Hazard Codes ]

Xn
[Risk Statements ]

36/38
[Safety Statements ]

26-36-61
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

Cholera Toxin B subunit has been used:
  • for macrophage stimulation and i.p. injection in a study to determine the endotoxin sensitivity of Caspase-4.
  • in transganglionic and retrograde tract-tracing method combined with dual-immunofluorescence histochemistry of adult rat Vmes neuron cells.
[General Description]

The advantage of this product over the native CTXB is that it has no traces of Vibrio cholera, and no contamination of the highly toxic Cholera toxin A subunit. This product is expressed in human HEK 293 cells as a C-terminally his-tagged protein with a calculated molecular mass of 13 kDa (amino acids Thr22-Asn124).
[Biochem/physiol Actions]

Cholera Toxin B subunit stimulates both systemic and mucosal antibody production in animals and humans. CTB functions as an oral subunit vaccine for cholera, which is associated with acute watery diarrhoea.
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