| Identification | Back Directory | [Name]
RAMOSETRON | [CAS]
132036-88-5 | [Synonyms]
Nasea
Ibsetron
Nor-YM 060
RAMOSETRON
Unii-7zro0sc54y
Ramosetron [inn]
(-)-(R)-1-Methylindol-3-yl 4,5,6,7-tetrahydro-5-benzimidazolylketone
(1-methyl-3-indolyl)-[(5R)-4,5,6,7-tetrahydro-3H-benzimidazol-5-yl]methanone
(R)-5α-[(1-Methyl-1H-indol-3-yl)carbonyl]-4,5,6,7-tetrahydro-1H-benzimidazole
(R)-5-[(1-METHYLINDOLE-3-YL)CARBONYL]-4,5,6,7-TETRAHYDRO-1H-BEZIMIDAZOLE, 98+%
(5R)-5α-[(1-Methyl-1H-indole-3-yl)carbonyl]-4,5,6,7-tetrahydro-1H-benzimidazole
(1-Methyl-1H-indol-3-yl)[[(5R)-4,5,6,7-tetrahydro-1H-benzimidazol]-5α-yl] ketone
(R)-(1-Methyl-1H-indol-3-yl)(4,5,6,7-tetrahydro-1H-benzo[d]imidazol-6-yl)methanone
Methanone, (1-methyl-1H-indol-3-yl)[(6R)-4,5,6,7-tetrahydro-1H-benzimidazol-6-yl]-
Methanone, (1-methyl-1H-indol-3-yl)(4,5,6,7-tetrahydro-1H-benzimidazol-5-yl)-, (R)-
Methanone, (1-methyl-1H-indol-3-yl)[(5R)-4,5,6,7-tetrahydro-1H-benzimidazol-5-yl]- (9CI) | [Molecular Formula]
C17H17N3O | [MDL Number]
MFCD00868551 | [MOL File]
132036-88-5.mol | [Molecular Weight]
279.34 |
| Chemical Properties | Back Directory | [alpha ]
D20 -16.5° (c 1.13 in methanol) | [Boiling point ]
579.7±50.0 °C(Predicted) | [density ]
1.33±0.1 g/cm3(Predicted) | [pka]
14.53±0.40(Predicted) | [InChI]
InChI=1S/C17H17N3O/c1-20-9-13(12-4-2-3-5-16(12)20)17(21)11-6-7-14-15(8-11)19-10-18-14/h2-5,9-11H,6-8H2,1H3,(H,18,19)/t11-/m1/s1 | [InChIKey]
NTHPAPBPFQJABD-LLVKDONJSA-N | [SMILES]
C(C1C2=C(N(C)C=1)C=CC=C2)([C@H]1CC2NC=NC=2CC1)=O |
| Hazard Information | Back Directory | [Uses]
Ramosetron is a serotonin 5HT3 receptor antagonist. | [Definition]
ChEBI: Ramosetron is a member of indoles. | [in vivo]
Ramosetron (0.01-0.1 mg/kg, p.o., twice daily for 5 days) Ameliorates 5-fluorouracil (5-FU) (HY-90006)-induced intestinal mucositis in C57BL/6 mice[2]. | [IC 50]
5-HT3 Receptor |
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