| Identification | Back Directory | [Name]
2,5-dioxopyrrolidin-1-yl pent-4-ynoate | [CAS]
132178-37-1 | [Synonyms]
Propargyl-C1-NHS ester
Succinimidyl 4-Pentynoate
4-Pentynoic acid NHS ester
4-Pentynoic acid succinimidyl ester
2,5-dioxopyrrolidin-1-yl pent-4-ynoate
4-Pentynoic acid, 2,5-dioxo-1-pyrrolidinyl ester | [Molecular Formula]
C9H9NO4 | [MDL Number]
MFCD22577791 | [MOL File]
132178-37-1.mol | [Molecular Weight]
195.17 |
| Chemical Properties | Back Directory | [Melting point ]
71 °C | [Boiling point ]
301.7±44.0 °C(Predicted) | [density ]
1.31±0.1 g/cm3(Predicted) | [storage temp. ]
-20°C, sealed storage, away from moisture and light | [solubility ]
DMSO: 2 mg/mL, clear | [form ]
Solid | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Propargyl-C1-NHS ester is a nonclaevable linker for antibody-agent-conjugation (ADC). Propargyl-C1-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | [IC 50]
Non-cleavable Linker |
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