ChemicalBook--->CAS DataBase List--->1322598-09-3

1322598-09-3

1322598-09-3 Structure

1322598-09-3 Structure
IdentificationBack Directory
[Name]

CATPB
[CAS]

1322598-09-3
[Synonyms]

CATPB
CATPB >=98% (HPLC)
(S)-3-(2-(3-Chlorophenyl)acetamido)-4-(4-(trifluoromethyl)phenyl)butanoic acid
Benzenebutanoic acid, β-[[2-(3-chlorophenyl)acetyl]amino]-4-(trifluoromethyl)-, (βS)-
[Molecular Formula]

C19H17ClF3NO3
[MDL Number]

MFCD30474718
[MOL File]

1322598-09-3.mol
[Molecular Weight]

399.79
Chemical PropertiesBack Directory
[Boiling point ]

579.3±50.0 °C(Predicted)
[density ]

1.353±0.06 g/cm3(Predicted)
[storage temp. ]

2-8°C
[solubility ]

Soluble in DMSO
[form ]

powder
[pka]

4.24±0.10(Predicted)
[color ]

white to beige
Hazard InformationBack Directory
[Uses]

CATPB (cas# 1322598-09-3) is a useful research chemical.CATPB was used to prepare fluorescent tracer for the free fatty acid receptor 2 (FFA2/GPR43).
[Biological Activity]

CATPB is an acetamidophenylbutanoate derivative with inverse agonist and antagonist activity against humanbut not mouse or ratFFA2 (GPR43). CATPB inhibits both constitutive and propionate (C3) -stimulated hFFA2 GTPγS incorporation (IC50 ~35 and 320 nMrespectively; [C3] = EC80~125 nM)as well as C3-induced hFFA2 G159E activity (IC50 ~400 nM). CATPB is shown to inhibit C3-induced intracellular ERK phosphorylation in hFFA2-expressing cells (IC50 ~3 μM against 10 mM C3).
[storage]

Store at -20°C
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