ChemicalBook--->CAS DataBase List--->13227-01-5

13227-01-5

13227-01-5 Structure

13227-01-5 Structure
IdentificationMore
[Name]

2-AMINO-2-(4-METHYLPHENYL)ACETIC ACID
[CAS]

13227-01-5
[Synonyms]

2-AMINO-2-(4-METHYLPHENYL)ACETIC ACID
4-METHYLPHENYL GLYCINE
AMINO(4-METHYLPHENYL)ACETIC ACID
AMINO-P-TOLYL-ACETIC ACID
DL-4-METHYLPHENYLGLYCINE
RARECHEM AK ML 0528
[Molecular Formula]

C9H11NO2
[MDL Number]

MFCD00665357
[Molecular Weight]

165.19
[MOL File]

13227-01-5.mol
Chemical PropertiesBack Directory
[Melting point ]

256-257°
[Boiling point ]

306.8±30.0 °C(Predicted)
[density ]

1.200±0.06 g/cm3(Predicted)
[storage temp. ]

Keep in dark place,Inert atmosphere,Room temperature
[solubility ]

Acetonitrile: Slightly soluble: 0.1-1 mg/ml
[form ]

solid
[pka]

2.03±0.10(Predicted)
[color ]

White
[CAS DataBase Reference]

13227-01-5(CAS DataBase Reference)
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
[HazardClass ]

IRRITANT
[HS Code ]

2922498590
Hazard InformationBack Directory
[Uses]

2-Amino-2-(p-tolyl)acetic acid is used for optimizing azide skeleton, and is the intermediate in the synthesis of 1,3, 4-thiadiazole compounds. 1,3,4-thiadiazole compounds exhibit potential anti-cancer activity, and inhibit glutaminase (GLSI)[1][2].
[storage]

Store at -20°C
[References]

[1] Kalie A M, et al. Cytosolic Delivery of Proteins by Bioreversible Esterification. JAmChem. 2017. 139(41):14396–14398.
[2] Finlay MRV, et al. Preparation of 1,3,4-thiadiazole compounds and their use in treating cancer: World Intellectual Property Organization, WO2017093301[P]. 2017-06-08.
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