| Identification | More | [Name]
2-AMINO-2-(4-METHYLPHENYL)ACETIC ACID | [CAS]
13227-01-5 | [Synonyms]
2-AMINO-2-(4-METHYLPHENYL)ACETIC ACID
4-METHYLPHENYL GLYCINE
AMINO(4-METHYLPHENYL)ACETIC ACID
AMINO-P-TOLYL-ACETIC ACID
DL-4-METHYLPHENYLGLYCINE
RARECHEM AK ML 0528 | [Molecular Formula]
C9H11NO2 | [MDL Number]
MFCD00665357 | [Molecular Weight]
165.19 | [MOL File]
13227-01-5.mol |
| Chemical Properties | Back Directory | [Melting point ]
256-257° | [Boiling point ]
306.8±30.0 °C(Predicted) | [density ]
1.200±0.06 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Inert atmosphere,Room temperature | [solubility ]
Acetonitrile: Slightly soluble: 0.1-1 mg/ml | [form ]
solid | [pka]
2.03±0.10(Predicted) | [color ]
White | [CAS DataBase Reference]
13227-01-5(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Uses]
2-Amino-2-(p-tolyl)acetic acid is used for optimizing azide skeleton, and is the intermediate in the synthesis of 1,3, 4-thiadiazole compounds. 1,3,4-thiadiazole compounds exhibit potential anti-cancer activity, and inhibit glutaminase (GLSI)[1][2]. | [storage]
Store at -20°C | [References]
[1] Kalie A M, et al. Cytosolic Delivery of Proteins by Bioreversible Esterification. JAmChem. 2017. 139(41):14396–14398.
[2] Finlay MRV, et al. Preparation of 1,3,4-thiadiazole compounds and their use in treating cancer: World Intellectual Property Organization, WO2017093301[P]. 2017-06-08. |
|
|