| Identification | Back Directory | [Name]
4-O-methylbutein | [CAS]
13323-67-6 | [Synonyms]
4-O-methylbutein
3,4',6'-Trihydroxy-4-methoxychalcone
3,2',4'-Trihydroxy-4-methoxychalcone
2-Propen-1-one, 1-(2,4-dihydroxyphenyl)-3-(3-hydroxy-4-methoxyphenyl)-
(E)-1-(2,4-dihydroxyphenyl)-3-(3-hydroxy-4-methoxyphenyl)prop-2-en-1-one | [Molecular Formula]
C16H14O5 | [MDL Number]
MFCD01696159 | [MOL File]
13323-67-6.mol | [Molecular Weight]
286.28 |
| Hazard Information | Back Directory | [Uses]
4-O-Methylbutein is a phenolic glucoside that can be isolated from Elsholtzia ciliata.4-O-Methylbutein exhibits neuroprotective effects against glutamate-induced HT22 cell death with an EC50 of 35.2 μM[1]. | [Definition]
ChEBI: 3,2',4'-Trihydroxy-4-methoxychalcone is a member of chalcones. | [References]
[1] Seo YH, et al. Chemical Constituents from the Aerial Parts of Elsholtzia ciliata and Their Protective Activities on Glutamate-Induced HT22 Cell Death. J Nat Prod. 2020 Oct 23;83(10):3149-3155. DOI:10.1021/acs.jnatprod.0c00756 |
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