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1337532-08-7

1337532-08-7 Structure

1337532-08-7 Structure
IdentificationBack Directory
[Name]

PERK-IN-3
[CAS]

1337532-08-7
[Synonyms]

PERK-IN-3
PERKIN3,PERK IN 3
Ethanone, 1-[5-(4-aminofuro[2,3-d]pyrimidin-5-yl)-2,3-dihydro-1H-indol-1-yl]-2-(2,5-difluorophenyl)-
[Molecular Formula]

C22H16F2N4O2
[MDL Number]

MFCD34469705
[MOL File]

1337532-08-7.mol
[Molecular Weight]

406.38
Chemical PropertiesBack Directory
[Boiling point ]

694.8±55.0 °C(Predicted)
[density ]

1.446±0.06 g/cm3(Predicted)
[pka]

4.73±0.40(Predicted)
Hazard InformationBack Directory
[Uses]

PERK-IN-3 is a potent PERK inhibitor with an IC50 of 7.4 nM[1].
[References]

[1] Axten JM , et al. Discovery of 7-methyl-5-(1-{[3-(trifluoromethyl)phenyl]acetyl}-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (GSK2606414), a potent and selective first-in-class inhibitor of protein kinase R (PKR)-like endoplasmic reticul DOI:10.1021/jm300713s
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