| Identification | Back Directory | [Name]
Folitixorin Calcium | [CAS]
133978-75-3 | [Synonyms]
Folitixorin Calcium
Folic Acid Impurity 13 Calcium Salt | [Molecular Formula]
C20H25CaN7O6 | [MDL Number]
MFCD30747913 | [MOL File]
133978-75-3.mol | [Molecular Weight]
499.54 |
| Hazard Information | Back Directory | [Uses]
Folitixorin calcium is a cofactor and an analog of leucovorin. Folitixorin calcium is a promising agent for modulation of 5-FU cytotoxicity in adjuvant cancer research[1][2]. | [References]
[1] Costantini CL, et al. Resection of hepatic metastasis after 5-fluorouracil and cofactor for colon cancer. Hepatogastroenterology. 2009;56(91-92):645-649. PMID:19621672
[2] Carlsson G, et al. 5-fluorouracil (5-FU) and 5,10-methylene tetrahydrofolate (5,10-CH2FH4) as adjuvant therapy in an experimental rodent colon carcinoma model. Anticancer Res. 1997;17(5A):3671-3674. PMID:9413221
[3] Botto LD, et al. 5,10-Methylenetetrahydrofolate reductase gene variants and congenital anomalies: a HuGE review. Am J Epidemiol. 2000;151(9):862-877. DOI:10.1093/oxfordjournals.aje.a010290 |
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