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134044-97-6

134044-97-6 Structure

134044-97-6 Structure
IdentificationBack Directory
[Name]

aciculatin
[CAS]

134044-97-6
[Synonyms]

aciculatin
4H-1-Benzopyran-4-one, 8-(2,6-dideoxy-β-D-ribo-hexopyranosyl)-5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-
[Molecular Formula]

C22H22O8
[MOL File]

134044-97-6.mol
[Molecular Weight]

414.41
Chemical PropertiesBack Directory
[LogP]

1.928 (est)
Hazard InformationBack Directory
[Description]

Aciculatin, a natural compound extracted from the medicinal herb Chrysopogon aciculatus, shows potent anti-cancer potency. Aciculatin treatment induces cell cycle arrest and apoptosis via inhibition of MDM2 expression, thereby inducing p53 accumulation without significant DNA damage and genome toxicity.
[Definition]

ChEBI: Aciculatin is a member of flavonoids and a C-glycosyl compound.
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