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134234-04-1

134234-04-1 Structure

134234-04-1 Structure
IdentificationBack Directory
[Name]

(1S,4R)-4-Amino-2-cyclopenten-1-carboxylic Acid Hydrochloride
[CAS]

134234-04-1
[Synonyms]

Peramivir Impurity 14 HCl
(1S,4R)-4-Amino-2-cyclopenten-1-carboxylic Acid
(1S,4R)-4-Amino-2-cyclopentene-1-carboxylic acid
Cis(1S,4R)-4-aMino-2-Cyclopentene-1-carboxylic acid
2-Cyclopentene-1-carboxylic acid, 4-aMino-, (1S,4R)-
2-Cyclopentene-1-carboxylicacid,4-amino-,(1S,4R)-(9CI)
(1S,4R)-4-Amino-2-cyclopenten-1-carboxylic Acid Hydrochloride
[Molecular Formula]

C6H9NO2
[MOL File]

134234-04-1.mol
[Molecular Weight]

127.14
Chemical PropertiesBack Directory
[Melting point ]

>260 °C (decomp)(Solv: water (7732-18-5); acetone (67-64-1))
[Boiling point ]

266.6±40.0 °C(Predicted)
[density ]

1.248±0.06 g/cm3(Predicted)
[storage temp. ]

Keep in dark place,Inert atmosphere,Room temperature
[pka]

3.52±0.20(Predicted)
[InChI]

InChI=1S/C6H9NO2/c7-5-2-1-4(3-5)6(8)9/h1-2,4-5H,3,7H2,(H,8,9)/t4-,5+/m1/s1
[InChIKey]

VTCHZFWYUPZZKL-UHNVWZDZSA-N
[SMILES]

[C@H]1(C(O)=O)C[C@@H](N)C=C1
Hazard InformationBack Directory
[Uses]

(1S,4R)-4-Amino-2-cyclopenten-1-carboxylic Acid is a γ-aminobutyric acid mimetic drug that affect dopaminergic activity.
[Synthesis]

Dissolve 10g of (1S, 4R)-4-aminocyclopent-2-ene-1-carboxylic acid methyl ester tartrate in 50mL of methanol, add triethylamine to neutralize to Ph6-7, add 10mL of water and cool to -20 , 5mL of lithium hydroxide aqueous solution (containing 0.16g of lithium hydroxide) was added dropwise, immediately after the reaction was neutralized with acetic acid to pH 3-4, the organic solvent was vortexed and diluted with tetrahydrofuran, the salt was filtered off and vortexed to obtain (1S,4R)-4-Amino-2-cyclopenten-1-carboxylic Acid Hydrochloride 3.6 g, yield 83.7%.
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