| Identification | More | [Name]
D-KYNURENINE | [CAS]
13441-51-5 | [Synonyms]
D-2-AMINO-4-[2-AMINOPHENYL]-4-OXOBUTANOIC ACID
D-KYNURENINE
D-kynurenine free base
β-Anthraniloyl-D-alanine
(2R)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid
β-Anthraniloyl-D-alanine, D-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid
(R)-α,2-Diamino-γ-oxobenzenebutanoic acid | [Molecular Formula]
C10H12N2O3 | [MDL Number]
MFCD00133224 | [Molecular Weight]
208.21 | [MOL File]
13441-51-5.mol |
| Chemical Properties | Back Directory | [Boiling point ]
466.6±45.0 °C(Predicted) | [density ]
1.343±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
Water:5.0(Max Conc. mg/mL);24.01(Max Conc. mM) | [form ]
A crystalline solid | [pka]
2.21±0.23(Predicted) | [color ]
Light yellow to yellow | [Optical Rotation]
Consistent with structure | [Major Application]
cell analysis | [InChI]
1S/C10H12N2O3/c11-7-4-2-1-3-6(7)9(13)5-8(12)10(14)15/h1-4,8H,5,11-12H2,(H,14,15)/t8-/m1/s1 | [InChIKey]
YGPSJZOEDVAXAB-MRVPVSSYSA-N | [SMILES]
N[C@H](CC(=O)c1ccccc1N)C(O)=O | [CAS DataBase Reference]
13441-51-5(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Uses]
D-Kynurenine is a metabolite of D-tryptophan that is also a bioprecursor of two neuroactive compounds kynurenic acid (KYNA) and 3-hydroxykynurenine. | [Definition]
ChEBI: A kynurenine that has D configuration. | [Biochem/physiol Actions]
D-Kynurenine may be used along with L-kynurenine to assess the specificity and kinetics of kynurenine metabolizing enzymes. D-Kynurenine is used to study the selectivity and activity of the G protein-coupled receptor, GPR109B. D-Kynurenine is used as a substrate in a fluorometric assay of D-amino acid oxidase. |
|
|