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134444-58-9

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134444-58-9 Structure

134444-58-9 Structure
IdentificationBack Directory
[Name]

Adenosine, 2'-deoxy-2'-fluoro-N-methyl-
[CAS]

134444-58-9
[Synonyms]

2’-Deoxy-2’-fluoro-N6-methyladensoine
Adenosine, 2'-deoxy-2'-fluoro-N-methyl-
[Molecular Formula]

C11H14FN5O3
[MOL File]

134444-58-9.mol
[Molecular Weight]

283.26
Chemical PropertiesBack Directory
[Boiling point ]

605.5±65.0 °C(Predicted)
[density ]

1.80±0.1 g/cm3(Predicted)
[pka]

12.61±0.70(Predicted)
Hazard InformationBack Directory
[Uses]

2′-Deoxy-2′-fluoro-N-methyladenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
[References]

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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