| Identification | Back Directory | [Name]
WAY 100289 | [CAS]
136013-69-9 | [Synonyms]
WAY 100289
endo-N-<<(8-methyl-8-azabicyclo<3.2.1>octan-3-yl)amino>carbonyl>-2-(cyclopropylmethoxy)benzamide
Benzamide, 2-(cyclopropylmethoxy)-N-[[[(3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl]amino]carbonyl]- | [Molecular Formula]
C20H27N3O3 | [MOL File]
136013-69-9.mol | [Molecular Weight]
357.45 |
| Hazard Information | Back Directory | [Uses]
WAY-100289 is an orally active antagonist for 5-HT3 receptor, that exhibits high affinity to the isolated rat vagus nerves with pA2 of 8.9. WAY-100289 inhibits the Bezold-Jarisch reflex in anesthetized and awake rats[1]. | [IC 50]
5-HT3 Receptor | [References]
[1] Rhodes K F, et al. WAY 100289: Pharmacological profile of a novel 5‐HT3 receptor antagonist[J]. Drug development research, 1993, 28(2): 128-140. |
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| Company Name: |
BOC Sciences
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| Tel: |
16314854226 |
| Website: |
www.bocsci.com |
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