| Identification | More | [Name]
Ketanserin | [CAS]
74050-98-9 | [Synonyms]
3-[2-[4-(4-fluorobenzoyl)-1-piperidinyl]ethyl]-2,4[1h,3h]-quinazolinedione
KETANSERIN
3-[2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl]-2，4-(IH，3H)-quinazolinedione
Ket
Ketensin
Perketan
R-49945
Serefrex
Serepress
Sufrexal
Taseron
2,4(1H,3H)-Quinazolinedione, 3-[2-[4-(4-fluorobenzoyl)-1-piperidinyl]ethyl]-
3-[2-[4-(4-Fluorobenzoyl)piperidin-1-yl]ethyl]-1H-quinazoline-2,4-dione
3-[2-[4-(4-Fluorobenzoyl)piperidin-1-yl]ethyl]-2,4(1H,3H)-quinazolinedione
3-[2-[4-(4-Fluorobenzoyl)piperidino]ethyl]-2,4(1H,3H)-quinazolinedione
Ketanserine | [EINECS(EC#)]
277-680-2 | [Molecular Formula]
C22H22FN3O3 | [MDL Number]
MFCD00083392 | [Molecular Weight]
395.43 | [MOL File]
74050-98-9.mol |
| Hazard Information | Back Directory | [Description]
Ketanserin is an antihypertensive agent with antagonist properties at both the
serotonin-S2 and α1-adrenergic receptors. Its mechanism of action, while still
controversial, may involve interactions at both of these loci. | [Chemical Properties]
Off-White Solid | [Originator]
Janssen (Belgium) | [Uses]
An antihypertensive, with affinity for multiple GPCR receptors. | [Uses]
receptor antagonist | [Definition]
ChEBI: A member of the class of quinazolines that is quinazoline-2,4(1H,3H)-dione which is substituted at position 3 by a 2-[4-(p-fluorobenzoyl)piperidin-1-yl]ethyl group. | [Brand name]
SEREFREX | [Purification Methods]
It has been purified by recrystallisation from 4-methyl-3-pentanone [Peeters et al. Cryst Structure Commun 11 375 1982, Kacprowicz et al. J Chromatogr 272 417 1983, Davies et al. J Chromatogr 275 232 1983]. It is an antihypertensive. |
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J & K SCIENTIFIC LTD.
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Jia Xing Isenchem Co.,Ltd
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0573-85285100 18627885956 |
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