| Identification | More | [Name]
TOTU | [CAS]
136849-72-4 | [Synonyms]
O-(CYANO(ETHOXYCARBONYL)METHYLENAMINO)-1,1,3,3-TETRAMETHYLURONIUM TETRAFLUOROBORATE
O-[(ETHOXYCARBONYL)CYANOMETHYLENAMINO]-N,N,N',N'-TETRAMETHYLURONIUM TETRAFLUOROBORATE
O-[(ETHOXYCARBONYL)-CYANOMETHYLENEAMINO]-1,1,3,3-TETRAMETHYLURONIUM TETRAFLUOROBORATE
O-((Ethoxycarbonyl)cyanomethyleneamino)-N,N,N',N'-tetramethyluronium BF4
O-[(ETHOXYCARBONYL)CYANOMETHYLENEAMINO]-N,N,N',N'-TETRAMETHYLURONIUM TETRAFLUOROBORATE
O-[(ETHOXYCARBOXYL)CYANOMETHYLENEAMINO]-N,N,N',N'-TETRAMETHYLURONIUM TETRAFLUOROBORATE
TOTU
HOBT(MONOHYDROUS)
O-[(Ethoxycarbonyl)cyanomethylenamino]-N,N,N',N'-tetramethyluronium tetrafluorob
O-[(ETHOXYCARBONYL)CYANOMETHYLENAMINO]-N,N,N',N'-TETRAMETHYL
TOTU:O-[(ETHOXYCARBONYL)CYANOMETHYLENAMINO]-N,N,N',N'-TETRAMETHYLURONIUM TETRAFLUOROBORATE
O-[(Ethoxycarbonyl)cyanomethylenamino]-N,N,N',N'-t
O-[(ETHOXYCARBONYL)CYANOMETHYLENAMINO]-N,N,N',N'-TETRAMETHYLURONIUM TETRAFLUORIDE
O-Cyanoethoxycarbonylmethylideneamino-1,1,3,3-tetr
2-CYANOETHOXYCARBONYLMETHYLIDENEAMINO-1,1,3,3-TETRAMETHYLURONIUMTETRAFLUOROBORATE
O-[(ETHOXYCARBONYL) CYANOMETHYLENAMINO] N,N,N'',N''-TETRAMETHYLURONIUM TETRAFLUOROBORATE (TOTU)
O-((ETHOXYCARBONYL)CYANOMETHYLENEAMINO)-N,N,N'',N''-TETRAMETHYLURONIUM TETRAFLUOROBORATE(TOTU)
TOTT
TOTU (O-[(ETHOXYCARBONYL)-CYANOMETHYLENEAMINO]-1,1,3,3-TETRAMETHYLURONIUM TETRAFLUOROBORATE)
O-(Ethoxycarbonyl)cyanomethylenaminoü-N,N,N',N'-tetramethyluronium tetrafluoroborate, 97% | [EINECS(EC#)]
629-020-3 | [Molecular Formula]
C10H17BF4N4O3 | [MDL Number]
MFCD00192127 | [Molecular Weight]
328.07 | [MOL File]
136849-72-4.mol |
| Chemical Properties | Back Directory | [Appearance]
white to yellowish crystalline powder | [Melting point ]
145 °C (dec.)(lit.) | [storage temp. ]
2-8°C
| [solubility ]
Soluble in water or 1% acetic acid | [form ]
Crystalline Powder | [color ]
White to yellow | [Sensitive ]
Moisture Sensitive | [Major Application]
peptide synthesis | [InChI]
InChI=1S/C10H17N4O3.BF4/c1-6-16-9(15)8(7-11)12-17-10(13(2)3)14(4)5;2-1(3,4)5/h6H2,1-5H3;/q+1;-1/b12-8-; | [InChIKey]
PZOBERLGEQHZDV-BPWZRWDXSA-M | [SMILES]
C(=[N+](/C)\C)(\N(C)C)/O/N=C(/C#N)\C(=O)OCC.[B-](F)(F)(F)F | [CAS DataBase Reference]
136849-72-4(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S37/39:Wear suitable gloves and eye/face protection . | [RIDADR ]
1759 | [WGK Germany ]
3
| [F ]
8-10-21 | [HazardClass ]
8 | [PackingGroup ]
III | [HS Code ]
29280000 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Oral
Eye Dam. 1
Skin Sens. 1A
STOT SE 3 | [Toxicity]
LD50 orally in Rabbit: 500 - 650 mg/kg |
| Hazard Information | Back Directory | [Chemical Properties]
white to yellowish crystalline powder | [Uses]
Reactant for:
Watson-Crick pairing of oligonucleotides
Esterification of nucleosides to solid phase supports
Reagent for:
Synthesis of selective integrin avβ3 antagonists
Design and synthesis of double stranded DNA libraries
Preparation of conformationally contrained β-amino acid derivatives
Synthesis and application of methyleneoxy pseudopeptide building blocks | [reaction suitability]
reaction type: Coupling Reactions |
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