| Identification | Back Directory | [Name]
4H-1,3,4-Thiadiazine-2-carboxamide, N-(2,4-difluorophenyl)-4-[(3-ethoxy-4-hydroxyphenyl)methyl]-5,6-dihydro-5-oxo- | [CAS]
1370706-59-4 | [Synonyms]
CL55
CL-55
CL 55
4H-1,3,4-Thiadiazine-2-carboxamide, N-(2,4-difluorophenyl)-4-[(3-ethoxy-4-hydroxyphenyl)methyl]-5,6-dihydro-5-oxo- | [Molecular Formula]
C19H17F2N3O4S | [MOL File]
1370706-59-4.mol | [Molecular Weight]
421.42 |
| Hazard Information | Back Directory | [Description]
CL-55 is a novel T3SS inhibitor; Antichlamydial agent. | [Uses]
CL-55 is an inhibitor for type three secretion system of Chlamydia trachomatis, that blocks the effector molecules delivery of bacteria into host cells. CL-55 ameliorates the C. trachomatis infection and inflammation in mice[1]. | [References]
[1] Koroleva EA, et al., Small molecule inhibitor of type three secretion suppresses acute and chronic Chlamydia trachomatis infection in a novel urogenital Chlamydia model. Biomed Res Int. 2015;2015:484853. DOI:10.1155/2015/484853 |
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