| Identification | More | [Name]
Boc-O-tert-butyl-L-threonine | [CAS]
13734-40-2 | [Synonyms]
BOC-L-THR(TBU)-OH
BOC-O-T-BUTYL-L-THREONINE
BOC-O-TERT-BUTYL-L-THREONINE
BOC-THR(BUT)-OH
BOC-THREONINE(TBU)-OH
BOC-THR(TBU)-OH
N-ALPHA-T-BOC-O-T-BUTYL-L-THREONINE
N-ALPHA-T-BUTOXYCARBONYL-O-T-BUTYL-L-THREONINE
N-ALPHA-TERT-BUTYLOXYCARBONYL-O-TERT-BUTYL-L-THREONINE
N-T-boc-O-T-butyl-L-threonine
N-ALPHA-T-BUTYLOXYCARBONYL-O-T-BUTYL-L-THREONINE
NALPHA-tert-Butoxycarbonyl-O-tert-butyl-L-threonine
N-tert-Butoxycarbonyl-O-t.-butyl-L-threonine
N-(tert-butoxycarbonyl)-O-tert-butyl-L-threonine | [Molecular Formula]
C13H25NO5 | [MDL Number]
MFCD00151115 | [Molecular Weight]
275.34 | [MOL File]
13734-40-2.mol |
| Chemical Properties | Back Directory | [Melting point ]
95-98 °C | [Boiling point ]
391.3±37.0 °C(Predicted) | [density ]
1.070±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C
| [solubility ]
Soluble in DMF. | [form ]
Solid | [pka]
3.53±0.10(Predicted) | [color ]
White to off-white | [Optical Rotation]
[α]20/D +3.6±0.5°, c = 2% in DMF | [BRN ]
4454820 | [Major Application]
peptide synthesis | [InChI]
1S/C13H25NO5/c1-8(18-12(2,3)4)9(10(15)16)14-11(17)19-13(5,6)7/h8-9H,1-7H3,(H,14,17)(H,15,16)/t8-,9+/m1/s1 | [InChIKey]
LKRXXARJBFBMCE-BDAKNGLRSA-N | [SMILES]
C[C@@H](OC(C)(C)C)[C@H](NC(=O)OC(C)(C)C)C(O)=O | [CAS DataBase Reference]
13734-40-2(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Uses]
N-Boc-O-tert-butyl-L-threonine is used as pharmaceutical intermediate. | [General Description]
Boc-Thr(t-Bu)-OH (N-Boc-O-tert-butyl-L-threonine) participates in the synthesis of 2,3-unsaturated glycosides, via reaction with per-O-acetylated glucal in the presence of Er(OTf)3 catalyst. | [reaction suitability]
reaction type: Boc solid-phase peptide synthesis |
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