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137735-25-2

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137735-25-2 Structure

137735-25-2 Structure
IdentificationBack Directory
[Name]

GSKpyridone
[CAS]

137735-25-2
[Synonyms]

GW844520
GSKpyridone
GW844520,GW-844520
3-chloro-2,6-dimethyl-5-[4-[4-(trifluoromethoxy)phenoxy]phenyl]-1H-pyridin-4-one
4(1H)-Pyridinone, 3-chloro-2,6-dimethyl-5-[4-[4-(trifluoromethoxy)phenoxy]phenyl]-
[Molecular Formula]

C20H15ClF3NO3
[MDL Number]

MFCD00907024
[MOL File]

137735-25-2.mol
[Molecular Weight]

409.79
Chemical PropertiesBack Directory
[Melting point ]

271-274 °C
[Boiling point ]

465.7±45.0 °C(Predicted)
[density ]

1.40±0.1 g/cm3(Predicted)
[pka]

10.06±0.69(Predicted)
Hazard InformationBack Directory
[Uses]

GW844520 is an orally active inhibitor of cytochrome bc1 complex. GW844520 can be used in malaria and anti-plasmodium related research[1].
[References]

[1] Xiang H,et al. Preclinical drug metabolism and pharmacokinetic evaluation of GW844520, a novel anti-malarial mitochondrial electron transport inhibitor. J Pharm Sci. 2006 Dec;95(12):2657-72. DOI:10.1002/jps.20681
137735-25-2 suppliers list
Company Name: SPIRO PHARMA  
Telephone:
Website: www.spiropharma.com.cn
Company Name: TargetMol Chemicals Inc.  
Telephone: 15002134094
Website: https://www.targetmol.cn/
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