ChemicalBook--->CAS DataBase List--->1379822-04-4

1379822-04-4

1379822-04-4 Structure

1379822-04-4 Structure
IdentificationBack Directory
[Name]

Suc-Ile-Glu(γ-pip)-Gly-Arg-pNA (hydrochloride)
[CAS]

1379822-04-4
[Synonyms]

Suc-Ile-Glu(γ-pip)-Gly-Arg-pNA (hydrochloride)
[Molecular Formula]

C34H53ClN10O10
[MDL Number]

MFCD34471158
[MOL File]

1379822-04-4.mol
[Molecular Weight]

797.31
Chemical PropertiesBack Directory
[solubility ]

DMF: 20mg/mL; DMSO: 3mg/mL; PBS (pH 7.2): 3mg/mL
[form ]

A solid
[color ]

White to off-white
[InChIKey]

UDIBETPIWZURPW-ONOGXCMKNA-N
[SMILES]

[C@@H](C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)NC1C=CC(N(=O)=O)=CC=1)(CCC(N1CCCCC1)=O)NC(=O)[C@H]([C@@H](C)CC)NC(=O)CCC(=O)O.Cl |&1:0,8,41,42,r|
Hazard InformationBack Directory
[Description]

Suc-Ile-Glu(γ-pip)-Gly-Arg-pNA is a colorimetric substrate for Factor Xa.1 Factor Xa preferentially binds to and cleaves the Ile-Glu(γ-pip)-Gly-Arg (IE(γ-pip)GR) peptide sequence to release p-nitroanilide (pNA), which can be quantified by colorimetric detection at 405 nm as a measure of Factor Xa activity.
[Uses]

Suc-Ile-Glu(γ-pip)-Gly-Arg-pNA hydrochloride is a factor Xa specific chromogenic substrate[1].
[References]

1. Yonghua, X. Suc Ile Glu (γ Pip) Gly Arg pNAHCl preparation method ,(2017).
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