| Identification | Back Directory | [Name]
SUC-LEU-TYR-AMC | [CAS]
94367-20-1 | [Synonyms]
SUC-LY-AMC
SUC-LEU-TYR-AMC
CALPAIN SUBSTRATE I
SUCCINYL-LEU-TYR-AMC
SUC-LEU-TYR-AMC USP/EP/BP
CALPAIN SUBSTRATE II, FLUOROGENIC
SUC-LEU-TYR-7-AMINO-4-METHYLCOUMARIN
N-SUCCINYL-LEU-TYR 4-METHYLCOUMARYL-7-AMIDE
N-SUCCINYL-LEU-TYR 7-AMIDO-4-METHYLCOUMARIN
succinyl-leucyl-tyrosyl-4-methyl-7-coumarylamide
Calpain Substrate II, Fluorogenic - CAS 94367-20-1 - Calbiochem
L-Tyrosinamide, N-(3-carboxy-1-oxopropyl)-L-leucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)- | [Molecular Formula]
C29H33N3O8 | [MDL Number]
MFCD00057900 | [MOL File]
94367-20-1.mol | [Molecular Weight]
551.59 |
| Chemical Properties | Back Directory | [storage temp. ]
-20°C | [solubility ]
DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml; Ethanol: 20 mg/ml | [form ]
Off-white solid | [color ]
off-white | [Sequence]
{Suc}-Leu-Tyr-{AMC} | [InChIKey]
VSWNAJAOJZXWBM-FTJGSZSVSA-N | [SMILES]
N([C@@H](C(CC)C)C(=O)NC(Cc3ccc(cc3)O)C(=O)Nc1cc2c(cc1)C(=CC(=O)O2)C)C(=O)CCC(=O)O |
| Hazard Information | Back Directory | [Uses]
Suc-Leu-Tyr-AMC is a fluorescent substrate for calpain I and II and papain that is used to measure the peptidase activity of the 20S proteasome. | [Definition]
ChEBI: Coumarin carrying a methyl group at C-4 and a succinyl-leucyl-tryrosyl side-chain at C-7. | [Biological Activity]
Cell permeable: no''Primary Target
Calpain -1 and -2''Product does not compete with ATP.''Reversible: no |
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Sigma-Aldrich
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