| Identification | Back Directory | [Name]
1,4-DIHYDRO-3-BETA-D-RIBOFURANOSYL-7H-PYRAZOLO[4,3-D]PYRIMIDIN-7-ONE | [CAS]
13877-76-4 | [Synonyms]
LAURUSIN
OHYAMYCIN
NSC106486
NSC-106486
NSC 106486
FORMYCIN B
3-(beta-d-ribofuranosyl)pyrazolo(4,3-d)6(h)-7-ketopyrimidine
1,4-Dihydro-3-β-D-ribofuranosyl-7H-pyrazolo[4,3-d]pyrimidin-7-one
3-β-D-Ribofuranosyl-1,4-dihydro-7H-pyrazolo[4,3-d]pyrimidine-7-one
3-d)pyrimidin-7-one,1,4-dihydro-3-beta-d-ribofuranosyl-7h-pyrazolo(
3-d)pyrimidin-7-one,1,6-dihydro-3-beta-d-ribofuranosyl-7h-pyrazolo(
7H-Pyrazolo[4,3-d]pyrimidin-7-one, 1,6-dihydro-3-β-D-ribofuranosyl-
1,4-DIHYDRO-3-BETA-D-RIBOFURANOSYL-7H-PYRAZOLO[4,3-D]PYRIMIDIN-7-ONE
7H-Pyrazolo4,3-dpyrimidin-7-one, 1,4-dihydro-3-.beta.-D-ribofuranosyl-
(1S)-1,4-Anhydro-1-C-[1,4-dihydro-7-oxo-7H-pyrazolo[4,3-d]pyrimidin-3-yl]-D-ribitol | [Molecular Formula]
C10H12N4O5 | [MDL Number]
MFCD00036828 | [MOL File]
13877-76-4.mol | [Molecular Weight]
268.23 |
| Chemical Properties | Back Directory | [Melting point ]
254-255 °C (decomp) | [Boiling point ]
777.5±60.0 °C(Predicted) | [density ]
2.18±0.1 g/cm3(Predicted) | [pka]
10.92±0.20(Predicted) |
| Hazard Information | Back Directory | [Uses]
Formycin B is an antibiotic, which exhibits antiparasitic activity against Leishmania. Formycin B exhibits toxicity to leukocytes, reversibly decreases neutrophils. Formycin B can be used in research about myeloid leukemia[1][2]. | [Definition]
ChEBI: Formycin B is a formycin. | [References]
[1] Rainey P, et al., Metabolism and mechanism of action of formycin B in Leishmania. Proc Natl Acad Sci U S A. 1983 Jan;80(1):288-92. DOI:10.1073/pnas.80.1.288
[2] Ishizuka M, et al., Biological studies on formycin and formycin B. J Antibiot (Tokyo). 1968 Jan;21(1):5-12. DOI:10.7164/antibiotics.21.5 |
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