| Identification | More | [Name]
3,5-Dimethylpyrazole | [CAS]
67-51-6 | [Synonyms]
3,5-DIMETHYL-1H-PYRAZOLE
3,5-DIMETHYLPYRAZOL
3,5-DIMETHYLPYRAZOLE
DMP
LABOTEST-BB LT00107055
TIMTEC-BB SBB004377
1(H)-3,5-Dimethylpyrazole
1H-Pyrazole,3,5-dimethyl-
3,5-dimethyl-1h-pyrazol
3,5-Dwumetylopirazolu
Pyrazole, 3,5-dimethyl-
TH 564
th564
U 6245
u6245
Pyrazole, 3,5-dimethyl-(6CI, 8CI)
DimethylPyrazole
3,5-Dimethylpyrazole,99%
3,5-Dimethylpyrazole, 98.50%
,5-Dimethylpyrazole | [EINECS(EC#)]
200-657-5 | [Molecular Formula]
C5H8N2 | [MDL Number]
MFCD00005243 | [Molecular Weight]
96.13 | [MOL File]
67-51-6.mol |
| Chemical Properties | Back Directory | [Appearance]
White crystal powder | [Melting point ]
105-108 °C (lit.) | [Boiling point ]
218 °C (lit.) | [density ]
0,884 g/cm3 | [refractive index ]
1.4739 (estimate) | [Fp ]
210°C | [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
methanol: 0.1 g/mL, clear
| [form ]
Crystalline Powder or Crystals | [pka]
15.12±0.10(Predicted) | [color ]
White to almost white | [PH]
6.7 (14g/l, H2O, 20℃) | [Water Solubility ]
Soluble in water, methanol 0.1 g/mL. | [Usage]
3,5-Dimethylpyrazole is used as intermediate for the manufacture of organic dyestuffs and photochemicals. Product Data Sheet | [Detection Methods]
GC | [BRN ]
106325 | [InChI]
1S/C5H8N2/c1-4-3-5(2)7-6-4/h3H,1-2H3,(H,6,7) | [InChIKey]
SDXAWLJRERMRKF-UHFFFAOYSA-N | [SMILES]
Cc1cc(C)[nH]n1 | [LogP]
1.010 | [CAS DataBase Reference]
67-51-6(CAS DataBase Reference) | [NIST Chemistry Reference]
1H-Pyrazole, 3,5-dimethyl-(67-51-6) | [EPA Substance Registry System]
67-51-6(EPA Substance) |
| Questions And Answer | Back Directory | [Preparation]
In a reaction vessel, add 1000 kg of water, 370 kg of acetylacetone, and an appropriate amount of glacial acetic acid. Then, add hydrazine hydrate dropwise, keeping the reaction temperature below 50°C. After all the hydrazine hydrate has been added, maintain the reaction at 50°C for 3 hours. Cool to 10°C, centrifuge, rinse, and vacuum dry to obtain 3,5-dimethylpyrazole. |
| Safety Data | Back Directory | [Symbol(GHS) ]
 
GHS07,GHS08 | [Signal word ]
Warning | [Hazard statements ]
H302-H373 | [Precautionary statements ]
P260-P264-P270-P301+P312-P314-P501 | [Hazard Codes ]
Xn,Xi | [Risk Statements ]
R22:Harmful if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [RTECS ]
UQ6477600
| [Hazard Note ]
Irritant | [TSCA ]
Yes | [REACH Registrations]
Active | [HazardClass ]
IRRITANT | [HS Code ]
29331990 | [Storage Class]
13 - Non Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Oral
STOT RE 2 |
| Raw materials And Preparation Products | Back Directory | [Raw materials]
1H-Pyrazole, 3,5-dimethyl-1-[2-[(4-methylphenyl)sulfonyl]ethyl]--->1-(4-methoxyphenyl)-3,5-dimethyl-1H-Pyrazole-->Ethyl 3-amino-4,6-dimethylthieno[2,3-b]pyridine-2-carboxylate-->1-Allyl-3 5-dimethylpyrazole 96-->1-Cyanoacetyl-3,5-dimethylpyrazole-->4-Bromo-3,5-dimethylpyrazole-->Semicarbazide hydrochloride-->Hydrazine hydrate-->2,3-Pentanedione | [Preparation Products]
4-Bromo-1,3,5-trimethyl-1H-pyrazole-->(1,3,5-Trimethyl-1H-pyrazol-4-yl)methylamine-->1,3,5-Trimethylpyrazole-->1,3,5-Trimethyl-1H-pyrazole-4-carboxaldehyde-->3,5-Pyrazoledicarboxylic acid-->1,3,5-Trimethyl-1H-pyrazole-4-carboxylic acid-->1H-Pyrazole-4-carbonyl chloride, 1,3,5-trimethyl- (9CI)-->1,4-Dioxaspiro[4.5]decan-8-one-->Diethyl 3,5-pyrazoledicarboxylate-->3,5-Dimethylpyrazole-1-methanol-->4-amino-3,5-dimethyl-pyrazol-->Benzenesulfonic acid, 3-[2-[4-[2-(3,5-dimethyl-1H-pyrazol-4-yl)diazenyl]-2,5-dimethoxyphenyl]diazenyl]-, sodium salt (1:1) |
| Hazard Information | Back Directory | [Chemical Properties]
White crystal powder | [Uses]
3,5-Dimethylpyrazole is used as intermediate for the manufacture of organic dyestuffs and photochemicals. Product Data Sheet | [Uses]
Common reagent for the preparation of pyrazolato ligated complexes.1,2 Also used to prepare N-1-substituted derivatives having antibacterial activity.3 | [Synthesis Reference(s)]
Journal of Heterocyclic Chemistry, 19, p. 373, 1982 DOI: 10.1002/jhet.5570190231
Organic Syntheses, Coll. Vol. 4, p. 351, 1963 | [Purification Methods]
Crystallise it from cyclohexane or water. [Barszez et al. J Chem Soc, Dalton Trans 2025 1986, Beilstein 23/5 V 110.] |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Alfa Aesar
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| Telephone: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
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