| Identification | Back Directory | [Name]
Calcium bis(cyclohexylsulphamate) | [CAS]
139-06-0 | [Synonyms]
cylan
dietil
cyclan
cacyclamate
calciumsucaryl
sucarylcalcium
kalziumzyklamate
CALCIUM CYCLAMATE
CYCLAMATE CALCIUM
Calcium Cycalmate
cyclamate,calciumsalt
cyclamicacidhemicalcium
calciumcyclohexylsulfamate
calciumcyclohexylsulphamate
calciumcyclohexanesulfamate
calciumcyclohexanesulphamate
calcium N-cyclohexylsulfamate
CYCLAMIC ACID HEMICALCIUM SALT
calcium bis(cyclohexylsulphamate)
calcium bis(N-cyclohexylsulfamate)
cyclohexylsulphamicacid,calciumsalt
cyclohexanesulfamicacid,calciumsalt
Cyclohexylsulfamic acid, calcium salt
cyclohexyl-sulfamicacicalciumsalt(2:1)
cyclohexanesulfamicacid,calciumsalt(2:1)
Sulfamicacid,cyclohexyl-,calciumsalt(2:1)
Bis(N-cyclohexylamidosulfuric acid)calcium salt
Calcium bis(cyclohexylsulphamate) ISO 9001：2015 REACH
Calcium cyclamate, Cyclohexanesulfamic acid hemicalcium salt | [EINECS(EC#)]
205-349-4 | [Molecular Formula]
C12H24CaN2O6S2 | [MDL Number]
MFCD00064942 | [MOL File]
139-06-0.mol | [Molecular Weight]
396.54 |
| Chemical Properties | Back Directory | [Appearance]
White crystals or powder; nearly odor-
less; very sweet taste. Freely soluble in water (solu-
tions are neutral to litmus); almost insoluble in alco-
hol, benzene, chloroform, and ether; p H (10% solu-
tion) 5.5–7.5. Sweetening power approximately 30
times that of sucrose.
| [Merck ]
13,1666 | [Cosmetics Ingredients Functions]
FRAGRANCE | [Uses]
Nonnutritive sweetener. | [EPA Substance Registry System]
Sulfamic acid, cyclohexyl-, calcium salt (2:1)(139-06-0) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
36/37/38 | [Safety Statements ]
26-36 | [RTECS ]
GV7100000 | [Safety Profile]
Poison by ingestion and
intravenous routes. Experimental
reproductive effects. Questionable
carcinogen with experimental tumorigenic
and neoplastigenic data. Human mutation
data reported. When heated to
decomposition it emits very toxic fumes of
SO, and NO,. See also CALCIUM
COMPOUNDS. | [Hazardous Substances Data]
139-06-0(Hazardous Substances Data) |
| Hazard Information | Back Directory | [Hazard]
Not permitted for use in foods and soft
drinks, because of suspected carcinogenicity.
| [Chemical Properties]
White crystals or powder; nearly odor-
less; very sweet taste. Freely soluble in water (solu-
tions are neutral to litmus); almost insoluble in alco-
hol, benzene, chloroform, and ether; p H (10% solu-
tion) 5.5–7.5. Sweetening power approximately 30
times that of sucrose. | [Originator]
Sucaryl Calcium,Abbott,US,1953 | [Manufacturing Process]
220 parts by weight, 2.22 mols, of cyclohexylamine and 57 parts by weight,
0,50 mol, of ammonium sulfamate were mixed at room temperature and
heated with agitation. At the end of one-half hour of heating the temperature
had reached 110°C and approximately one-half mol of ammonia had been
evolved. Heating was continued under reflux at 133°C for 22 additional hours.
A second half-mol of ammonia was liberated. The ammonia yield was 100%.
The reaction mixture was cooled to 100°C. To the mixture was added a water
slurry containing 20.3 parts by weight, 0.55 equivalent, of calcium hydroxide
and 700 parts by weight of water. Cyclohexylamine was then removed by
azeotropic distillation with water.
The amine which was recovered can be reused after drying.
The residue from the distillation was evaporated to dryness in a vacuum oven
at 50°C and the resulting product analyzed. The product weighing 105.5 parts
by weight, 0.488 equivalent, was obtained which is a 98% yield of the
technical calcium cyclohexylsulfamate dihydrate. | [Therapeutic Function]
Pharmaceutic aid |
|
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Alfa Chemistry
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https://www.alfa-chemistry.com |
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Merck KGaA
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Amfinecom Inc.
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+1 (804) 861-0001 |
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www.amfinecom.com |
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SIGMA-RBI
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www.sigma-aldrich.com |
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