| Identification | More | [Name]
3-[(1S)-1-(Dimethylaminoethyl)]phenol | [CAS]
139306-10-8 | [Synonyms]
3-[(1s)-1-(dimethylaminoethyl)]phenol
NAP 226-90
RIVASTIGMINE METABOLITE
(S)-3-1(-DIMETHYLAMINO)ETHYLPHENOL
3-((S)-1-DIMETHYLAMINO-ETHYL)-PHENOL
Rivastigmine Intermediate 3
Rivastigmine Intermediate 9
3-[(1S)1-(DIMETHYLAMINO)ETHYL]PHENOL(INTERMEDIATEOFRIVASTIGMINE)
(S)-3-(1-N,N-DIMETHY(AMINO)ETHYL PHENOL
(1S)-3-[-1-(Dimethylaminoethyl)]phenol
Rivastigmine-3-(1-(dimethylamino)ethyl)phenol | [EINECS(EC#)]
1308068-626-2 | [Molecular Formula]
C10H15NO | [MDL Number]
MFCD06656491 | [Molecular Weight]
165.23 | [MOL File]
139306-10-8.mol |
| Chemical Properties | Back Directory | [Appearance]
off-white to pale yellow crysta | [Melting point ]
87-88°C | [Boiling point ]
241℃ | [density ]
1.021 | [Fp ]
97℃ | [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
9.86±0.10(Predicted) | [color ]
White to Off-White | [Usage]
S-Enantiomer metabolite of Rivastigmine, a brain selective acetylcholinesterase inhibitor | [Major Application]
pharmaceutical (small molecule) | [InChI]
InChI=1S/C10H15NO/c1-8(11(2)3)9-5-4-6-10(12)7-9/h4-8,12H,1-3H3/t8-/m0/s1 | [InChIKey]
GQZXRLWUYONVCP-QMMMGPOBSA-N | [SMILES]
C1(O)=CC=CC([C@@H](N(C)C)C)=C1 | [CAS DataBase Reference]
139306-10-8(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Description]
NAP 226-90 is a metabolite of rivastigmine (Item No. 14270) that is formed by hydrolysis.1 | [Chemical Properties]
off-white to pale yellow crysta | [Uses]
NAP 226-90 (Rivastigmine EP Impurity A; Rivastigmin USP Related Compound C) is a S-Enantiomer metabolite of Rivastigmine, a brain selective acetylcholinesterase inhibitor. | [Uses]
S-Enantiomer metabolite of Rivastigmine, a brain selective acetylcholinesterase inhibitor | [storage]
Store at -20°C | [References]
[1] MD R J P. Clinical pharmacology of rivastigmine: a new-generation acetylcholinesterase inhibitor for the treatment of alzheimer’s disease[J]. Clinical therapeutics, 1998, 20 4: Pages 634-647. DOI: 10.1016/s0149-2918(98)80127-6 |
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J & K SCIENTIFIC LTD.
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