| Identification | Back Directory | [Name]
Dunnial | [CAS]
139726-29-7 | [Synonyms]
Dunnial
Dunnianol
5,5',5''-Triallyl-1,1':3',1''-terphenyl-2,2',2''-triol
[1,1':3',1''-Terphenyl]-2,2',2''-triol, 5,5',5''-tri-2-propen-1-yl- | [Molecular Formula]
C27H26O3 | [MDL Number]
MFCD20260870 | [MOL File]
139726-29-7.mol | [Molecular Weight]
398.49 |
| Chemical Properties | Back Directory | [Melting point ]
134-135 °C | [Boiling point ]
525.4±45.0 °C(Predicted) | [density ]
1.143±0.06 g/cm3(Predicted) | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
Powder | [pka]
8.79±0.48(Predicted) |
| Hazard Information | Back Directory | [Uses]
Dunnianol is a natural sesqui-neoligan with moderate antibacterial activity. Dunnianol inhibits Staphylococcus aureus and methicillin-resistant Staphylococcus aureus (MRSA). | [target]
NF-kB | NOS | ROS | [References]
[1] Yong Guo, et al. Discovery, Synthesis, and Biological Evaluation of Dunnianol-Based Mannich Bases against Methicillin-Resistant Staphylococcus aureus (MRSA). ACS Infect Dis. 2020 Sep 11;6(9):2478-2489. DOI:10.1021/acsinfecdis.0c00377 |
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