| Identification | Back Directory | [Name]
Tenuifoliside B | [CAS]
139726-36-6 | [Synonyms]
Tenuifoliside B
α-D-Glucopyranoside, 3-O-[(2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)-1-oxo-2-propen-1-yl]-β-D-fructofuranosyl, 6-(4-hydroxybenzoate)
3-O-[(2E)-3-(4-Hydroxy-3,5-dimethoxyphenyl)-1-oxo-2-propen-1-yl]-beta-D-fructofuranosyl alpha-D-glucopyranoside 6-(4-hydroxybenzoate) | [Molecular Formula]
C30H36O17 | [MDL Number]
MFCD00915287 | [MOL File]
139726-36-6.mol | [Molecular Weight]
668.6 |
| Chemical Properties | Back Directory | [Melting point ]
144-146 °C | [Boiling point ]
926.1±65.0 °C(Predicted) | [density ]
1.61±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
8.13±0.15(Predicted) | [color ]
White to yellow | [InChIKey]
HBYKIOIUVMDUIK-YCNVUVRCNA-N |
| Hazard Information | Back Directory | [Uses]
Tenuifoliside B, a component isolated from Polygalae Radix, inhibits potassium cyanide (KCN)-induced hypoxia and scopolamine-induced memory impairment. Tenuifoliside B shows potential cognitive improvement and cerebral protective effects. Tenuifoliside B has potential to become an anti-AD lead compound[1][2]. | [References]
[1] YongjiangWu, et al. Studies on the total synthesis of tenuifoliside B. Tetrahedron. 2017 Jun.
[2] Fumito KARAKIDA, et al. Cerebral Protective and Cognition-Improving Effects of Sinapic Acid in Rodents. Biol. Pharm. Bull. 30(3) 514-519 (2007). |
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