ChemicalBook--->CAS DataBase List--->139968-49-3

139968-49-3

139968-49-3 Structure

139968-49-3 Structure
IdentificationBack Directory
[Name]

bas 320i
[CAS]

139968-49-3
[Synonyms]

BAS3201
bas 320i
METAFLUMIZONE
Metaflumizone-d6
Metaflumizone [iso]
metaflumizone (bsi, pa iso)
Metaflumizone@100 μg/mL in Acetonitrile
Metaflumizone Solution in Acetonitrile, 100μg/mL
2μ-[2-(4-Cyanophenyl)-1-(α,α,α-trifluoro-m-tolyl)ethylidene]-4-(trifluoromethoxy)carbanilohydrazide
2-[2-(4-Cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]-N-[4-(trifluoromethoxy)phenyl]-hydrazinecarboxamide
Hydrazinecarboxamide,2-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]-N-[4-(trifluoromethoxy)phenyl]-
[EINECS(EC#)]

204-798-3
[Molecular Formula]

C24H16F6N4O2
[MDL Number]

MFCD08690508
[MOL File]

139968-49-3.mol
[Molecular Weight]

506.404
Chemical PropertiesBack Directory
[density ]

1.34±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMSO (Slightly), Methanol (Slightly, Heated)
[form ]

neat
[pka]

10.82±0.46(Predicted)
[color ]

Light yellow to yellow
[Major Application]

agriculture
environmental
[InChIKey]

MIFOMMKAVSCNKQ-QNKGDIEWSA-N
[SMILES]

FC(F)(F)Oc1ccc(NC(=O)N\N=C(/Cc2ccc(cc2)C#N)c3cccc(c3)C(F)(F)F)cc1
[LogP]

6.055 (est)
[EPA Substance Registry System]

Hydrazinecarboxamide, 2-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]-N-[4-(trifluoromethoxy)phenyl]- (139968-49-3)
Safety DataBack Directory
[RIDADR ]

UN 3077 9 / PGIII
[WGK Germany ]

WGK 3
[RTECS ]

MV1576452
[Storage Class]

11 - Combustible Solids
[Hazard Classifications]

Lact.
Repr. 2
STOT RE 2
Hazard InformationBack Directory
[Description]

Metaflumizone is a semicarbazone broad-spectrum insecticide. It has a low aqueous solubility, is non-volatile and a low potential for leaching to groundwater based on its chemical properties. It is persistent in soil and in water-sediment systems. It has a low mammalian toxicity and considered to have potential negative reproduction/developmental effects. It also has a high potential for bioaccumulation. It has a low to moderate toxicity to most birds, aquatic species, honeybees and earthworms.
[Chemical Properties]

Metaflumizone technical product appears as a white crystalline powder with a faint aromatic odor. Metaflumizone is a semicarbazone insecticide with low toxicity, environmental friendliness, and a low-risk systemic action.
[Uses]

Metaflumizone is a semicarbazone insecticide that works by blocking sodium channel in target insects resulting in paralyzation associated with blocking nerve activity. Metaflumizone is useful as a hea rtworm control treatment.
[Production Methods]

Metaflumizone is synthesised through a condensation reaction involving two key intermediates: m-trifluoromethylphenyl-4-nitrilebenzylketone and p-trifluoromethoxyphenylaminohydrazide. These compounds are combined in a reactor with a water-insoluble organic solvent and a suitable catalyst, then heated to temperatures between 80 DegC and 140 DegC for 1 to 3 hours. During the reaction, water is generated and removed by the solvent, which drives the reaction forward and improves yield. After completion, the mixture is cooled to between 0 and 30 DegC, and the product is isolated by filtration.
[Mechanism of action]

Broad-spectrum, attacks insect nervous system causing paralysis. Voltage-dependent sodium channel modulator.
[Veterinary Drugs and Treatments]

Metaflumizone is a new insecticide used for the treatment and control of fleas on dogs and cats. It blocks the influx of sodium required to propagate a nerve impulse along the axon and dendrite of the neuron causing a reduction in feeding, loss of coordination, paralysis and death of the flea.
[storage]

Store at -20°C
[Pesticide Type]

Insecticide; Veterinary substance
Spectrum DetailBack Directory
[Spectrum Detail]

Metaflumizone(139968-49-3)1HNMR
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