| Identification | More | [Name]
N,N'-Bis(phenylmethyl)-1,2-ethanediamine | [CAS]
140-28-3 | [Synonyms]
1 2-BIS(BENZYLAMINO)ETHANE
BENZATHINE
ETHYLENEDIAMINE-N N'-DIBENZYL
N,N'-BIS(PHENYLMETHYL)-1,2-ETHANEDIAMINE
N,N'-DIBENZYLETHYLENEDIAMINE
N'N-DIBENZYL-ETHYLENEDIAMINE
Benzatin
Dbed
n,n’-bis(phenylmethyl)-2-ethanediamine
n,n’-dibenzyl-ethylenediamin
N,N'-Dibenzyl-1,2-ethanediamine
N,N'-Dibenzyl-1,2-ethylenediamine
N,N'-Dibenzyl-ethane-1,2-diamine
USAF do-53
usafdo-53
1,2-di(benzylamino)ethane
Benzathine~1,2-Bis(benzylamino)ethane
N,N`-dibenzylethylendiamine
BENZATHINE 99%
1 2-BIS(BENZYLAMINO)ETHANE 99% | [EINECS(EC#)]
205-408-4 | [Molecular Formula]
C16H20N2 | [MDL Number]
MFCD00004771 | [Molecular Weight]
240.34 | [MOL File]
140-28-3.mol |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
R22:Harmful if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [RIDADR ]
2927 | [WGK Germany ]
3
| [RTECS ]
KV3325000
| [TSCA ]
Yes | [HazardClass ]
8 | [PackingGroup ]
III | [HS Code ]
29215990 | [Toxicity]
LD50 orl-mus: 388 mg/kg CNCRA6 52,579,68 |
| Hazard Information | Back Directory | [Chemical Properties]
light yellow liquid | [Uses]
N,N'-Dibenzylethylenediamine is an intermediate of cephalosporin and penicillin. | [Definition]
ChEBI: Benzathine is a diamine. It is a conjugate base of a benzathine(1+). | [Synthesis Reference(s)]
The Journal of Organic Chemistry, 55, p. 3209, 1990 DOI: 10.1021/jo00297a042 | [Safety Profile]
Poison by ingestion,intraperitoneal, and parenteral routes. When heated todecomposition it emits toxic vapors of NOx. | [Purification Methods]
Dissolve DBED in acid, extract with toluene, basify, extract it with Et2O, dry over solid KOH, evaporate and fractionate it in vacuo. The diacetate crystallises from H2O by addition of EtOH and has m 111o (solubility in H2O is ~25%). The dihydrochloride has m 306-308o (from H2O) and the dipicrate has m 212o(dec) (from H2O). [Frost et al., J Am Chem Soc 71 3842 1949, Beilstein 12 H 1067, 12 III 2304.] |
|
|