ChemicalBook--->CAS DataBase List--->1404437-62-2

1404437-62-2

1404437-62-2 Structure

1404437-62-2 Structure
IdentificationBack Directory
[Name]

ML281
[CAS]

1404437-62-2
[Synonyms]

ML281
CS-2166
ML 281;ML-281
N-(4-isopropyl-2-(3-oxo-3,4-dihydroquinoxalin-2-yl)phenyl)thiophene-2-carboxamide
N-[2-(3,4-Dihydro-3-oxo-2-quinoxalinyl)-4-(1-methylethyl)phenyl]-2-thiophenecarboxamide
2-Thiophenecarboxamide, N-[2-(3,4-dihydro-3-oxo-2-quinoxalinyl)-4-(1-methylethyl)phenyl]-
[Molecular Formula]

C22H19N3O2S
[MDL Number]

MFCD25976601
[MOL File]

1404437-62-2.mol
[Molecular Weight]

389.47
Chemical PropertiesBack Directory
[storage temp. ]

Keep in dark place,Sealed in dry,2-8°C
[solubility ]

DMF: 33 mg/ml; DMF:PBS (pH 7.2) (1:4): 0.2 mg/ml; DMSO: 20 mg/ml
[form ]

A crystalline solid
[color ]

White to off-white
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
Hazard InformationBack Directory
[Uses]

ML 281 is a potent and selective quinoxalinone-based inhibitor of STK33 effectively targeting KRAS-dependent cancers.
[Definition]

ChEBI: N-[2-(3-oxo-4H-quinoxalin-2-yl)-4-propan-2-ylphenyl]-2-thiophenecarboxamide is an aromatic amide.
[storage]

Store at +4°C
Spectrum DetailBack Directory
[Spectrum Detail]

ML281(1404437-62-2)1HNMR
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