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14046-64-1

14046-64-1 Structure

14046-64-1 Structure
IdentificationBack Directory
[Name]

BENSERAZIDE HYDROCHLORIDE
[CAS]

14046-64-1
[Synonyms]

RO 4-4602
BENOXACOR
Benzaerazide Hcl
BENSERAZIDE HYDROCHLORIDE 99%
DL-SERINE 2-[(2,3,4-TRIHYDROXYPHENYL)METHYL]HYDRAZIDE HCL
DL-SERINE 2[(2,3,4-TRIHYDROXYPHENYL)-METHYL] HYDRAZIDE HYDROCHLORIDE
2-amino-3-hydroxy-N'-(2,3,4-trihydroxybenzyl)propionohydrazide hydrochloride
2-amino-3-hydroxy-N'-[(2,3,4-trihydroxyphenyl)methyl]propanehydrazide hydrochloride
2-azanyl-3-hydroxy-N'-[(2,3,4-trihydroxyphenyl)methyl]propanehydrazide hydrochloride
[EINECS(EC#)]

238-991-9
[Molecular Formula]

C10H16ClN3O5
[MDL Number]

MFCD00078571
[MOL File]

14046-64-1.mol
[Molecular Weight]

293.7
Chemical PropertiesBack Directory
[solubility ]

H2O: 10 mg/mL
[form ]

solid
Safety DataBack Directory
[Hazard Codes ]

Xi
[Risk Statements ]

36/37/38
[Safety Statements ]

26-36
[WGK Germany ]

2
[RTECS ]

VT9632300
[Toxicity]

mouse,LD50,intraperitoneal,1700mg/kg (1700mg/kg),Kiso to Rinsho. Clinical Report. Vol. 11, Pg. 62, 1977.
Hazard InformationBack Directory
[Definition]

ChEBI: Benserazide hydrochloride is a hydrochloride that is the monohydrochloride salt of benserazide. An aromatic-L-amino-acid decarboxylase inhibitor (DOPA decarboxylase inhibitor) that does not enter the central nervous system, it is used as an adjunct to levodopa in the treatment of parkinsonism. By preventing the conversion of levodopa to dopamine in the periphery, it causes an increase in the amount of levodopa reaching the central nervous system and so reduces the required dose. Benserazide hydrochloride has no antiparkinson actions when given alone. It has a role as an antiparkinson drug, an EC 4.1.1.28 (aromatic-L-amino-acid decarboxylase) inhibitor and a dopaminergic agent. It contains a benserazide(1+).
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