| Identification | Back Directory | [Name]
2-Keto Crizotinib | [CAS]
1415558-82-5 | [Synonyms]
PF-06260182
2-Keto Crizotinib
Crizotinib impurity B
Crizotinib 2-Keto Impurity
KLXFBZLBBBMWAI-YNODCEANSA-N
Crizotinib metabolite hydrochloride salt
2-Piperidinone, 4-[4-[6-amino-5-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-3-pyridinyl]-1H-pyrazol-1-yl]- | [Molecular Formula]
C21H20Cl2FN5O2 | [MDL Number]
MFCD22124891 | [MOL File]
1415558-82-5.mol | [Molecular Weight]
464.32 |
| Chemical Properties | Back Directory | [Boiling point ]
679.9±55.0 °C(Predicted) | [density ]
1.53±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Chloroform (Slightly, Sonicated), DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
15.68±0.40(Predicted) | [color ]
Pale Beige to Light Beige |
| Hazard Information | Back Directory | [Uses]
2-Keto Crizotinib is an impurity of Crizotinib (C785000), a potent and selective dual inhibitor of mesenchymal-epithelial transition factor (c-MET) kinase and anaplastic lymphoma kinase (ALK). Crizotinib is a potential antitumor agent. |
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J & K SCIENTIFIC LTD.
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18210857532 18210857532 |
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https://www.jkchemical.com |
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Lynnchem
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http://www.lynnchem.com/ |
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AFINE CHEMICALS LIMITED
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+86-571-85134551 +86-18958018566 |
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www.afinechem.com/index.html |
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