ChemicalBook--->CAS DataBase List--->141750-63-2

141750-63-2

141750-63-2 Structure

141750-63-2 Structure
IdentificationBack Directory
[Name]

PITAVASTATIN LACTONE
[CAS]

141750-63-2
[Synonyms]

PITAVASTATIN LACTONE
Pitavastatin calcium impurity D
Pitavastatin Lactone DISCONTINUED
(4R,6S,E)-6-[2-[2-Cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]vinyl]tetrahydro-4-hydroxypyran-2-one
Pitavastatin calciuM interMediates to 5, (4R, 6S, E) -6 - [2 - cyclopropyl-4 - (4 - fluorophenyl) -3 - quinoline - yl - vinyl] -4 - hydroxy -3,4,5,6 - tetrahydro-2H-pyran-2 - one
[EINECS(EC#)]

1592732-453-0
[Molecular Formula]

C25H22FNO3
[MOL File]

141750-63-2.mol
[Molecular Weight]

403.45
Chemical PropertiesBack Directory
[Appearance]

White to Off-White Powder
[Melting point ]

92-95°C
[alpha ]

D32 +8.84° (c = 0.92 in chloroform)
[Boiling point ]

616.9±55.0 °C(Predicted)
[density ]

1.372±0.06 g/cm3(Predicted)
[pka]

13.25±0.40(Predicted)
Hazard InformationBack Directory
[Chemical Properties]

White to Off-White Powder
[Uses]

Lactone form of Pitavastatin; a HMG-CoA reductase inhibitor. Recent studies have shown that conversion between acid and lactone forms occurs in the body, drug-drug interaction should be considered on both acid and lactone forms.
Spectrum DetailBack Directory
[Spectrum Detail]

PITAVASTATIN LACTONE(141750-63-2)1HNMR
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