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1421366-99-5

1421366-99-5 Structure

1421366-99-5 Structure
IdentificationBack Directory
[Name]

2-Piperidinecarboxamide, 1-(2-oxo-2-phenylacetyl)-N-(3-phenylpropyl)-, (2S)-
[CAS]

1421366-99-5
[Synonyms]

ElteN378
2-Piperidinecarboxamide, 1-(2-oxo-2-phenylacetyl)-N-(3-phenylpropyl)-, (2S)-
[Molecular Formula]

C23H26N2O3
[MOL File]

1421366-99-5.mol
[Molecular Weight]

378.46
Chemical PropertiesBack Directory
[density ]

1.175±0.06 g/cm3(Predicted)
[form ]

Oil
[pka]

14.62±0.20(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Description]

ElteN378 is a novel potent fkbp12 ligand
[Uses]

ElteN378 is an inhibitors of FKBP12e. ElteN378 can be used in study Alzheimer disease, Parkinson disease, Amyotrophic Lateral Sclerosis, proliferation disorders and cancer[1].
[References]

[1] Martina MR, et al. The precise chemical-physical nature of the pharmacore in FK506 binding protein inhibition: ElteX, a New class of nanomolar FKBP12 ligands. J Med Chem. 2013 Feb 14;56(3):1041-51. DOI:10.1021/jm3015052
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