ChemicalBook--->CAS DataBase List--->142246-63-7

142246-63-7

142246-63-7 Structure

142246-63-7 Structure
IdentificationBack Directory
[Name]

5'-O-(4,4'-DIMETHOXYTRITYL)-5-FLUORODEOXYURIDINE-3'-(2-CYANOETHYL-N,N-DIISOPROPYL)PHOSPHORAMIDITE
[CAS]

142246-63-7
[Synonyms]

5-FLUORO-DU CEP
5-F-dU Phosphoramidite
5'-DMT-5-F-2'-dU Phosphoramidite
5'-DMT-5-F-2'-dU Phosphoramidite
5-fluorodeoxyuridine-ce*phosphoramidite for abi
5-O-DMTr-5-FLUORO-2-DEOXY-URIDINE-3-O-CE-AMIDITE
5-FLUORODEOXYURIDINE-CE PHOSPHORAMIDITE FOR CYCLONE
5'-O-DMT-5-Fluoro-2'-deoxyuridine-3'-CE phosphoramidite
N-blocked-5'-O-DMT CED fluorodeoxyuridine phosphoramidite
5-Fluoro-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyuridine-3'-cyanoethyl Phosphoramidite
5'-Dimethoxytrityl-5-fluoro-2'-deoxyUridine,3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
5'-O-(4,4'-DIMETHOXYTRITYL)-5-FLUORODEOXYURIDINE-3'-(2-CYANOETHYL-N,N-DIISOPROPYL)PHOSPHORAMIDITE
5'-O-(4,4'-DIMETHOXYTRITYL)-5-FLUORODEOXYURIDINE-3'-(2-CYANOETHYL-N,N-DIISOPROPYL)PHOSPHORAMIDITE
5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-5-fluoro-uridine 3'-[2-cyanoethylbis(1-methylethyl)phosphoramidite]
Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-5-fluoro-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite] (9CI)
(2R,3S,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(5-fluoro-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
[Molecular Formula]

C39H46FN4O8P
[MDL Number]

MFCD00274114
[MOL File]

142246-63-7.mol
[Molecular Weight]

748.78
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

DMSO: Sparingly Soluble: 1-10 mg/ml
Ethanol: Sparingly Soluble: 1-10 mg/ml
Hazard InformationBack Directory
[Uses]

5''-O-[Bis(4-methoxyphenyl)phenylmethyl]-2''-deoxy-5-fluoro-uridine 3''-[2-cyanoethylbis(1-methylethyl)phosphoramidite] is a nucleoside analog that may be effective in the treatment of breast cancer by influencing the expression of HER-2.
[References]

[1] QUANBING MOU. DNA Trojan Horses: Self-Assembled Floxuridine-Containing DNA Polyhedra for Cancer Therapy[J]. Angewandte Chemie, 2017, 129 41: 12702-12706. DOI: 10.1002/ange.201706301
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