| Identification | Back Directory | [Name]
Syncytial Virus Inhibitor-1 | [CAS]
1422496-79-4 | [Synonyms]
Syncytial Virus Inhibitor-1
Syncytial Virus Inhibitor 1,Syncytial Virus Inhibitor1
4-Quinolinamine, N-[(3-amino-3-oxetanyl)methyl]-2-(2,3-dihydro-1,1-dioxido-1,4-benzothiazepin-4(5H)-yl)-6-methyl- | [Molecular Formula]
C23H26N4O3S | [MDL Number]
MFCD32067924 | [MOL File]
1422496-79-4.mol | [Molecular Weight]
438.54 |
| Hazard Information | Back Directory | [Uses]
Syncytial Virus Inhibitor-1 is a potent, orally bioavailable respiratory syncytial virus (RSV) fusion inhibitor with EC50s of 0.002 μM, 0.004 μM, and 0.002 μM for RSV Long, RSV A2, and RSV B strains, respectively[1]. | [References]
[1] Zheng X, et al. Discovery of Benzoazepinequinoline (BAQ) Derivatives as Novel, Potent, Orally BioavailableRespiratory Syncytial Virus Fusion Inhibitors. J Med Chem. 2018 Nov 21;61(22):10228-10241. DOI:10.1021/acs.jmedchem.8b01394 |
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