| Identification | Back Directory | [Name]
L-701,324 | [CAS]
142326-59-8 | [Synonyms]
L-701
CS-2045
L-701,324
L-701,304
7-Chloro-4-hydroxy-3-(3-phenoxy)phenyl-2(H)-quinolinone
7-chloro-1-(4-hydroxy-3-phenoxyphenyl)quinolin-2(1H)-one
7-CHLORO-4-HYDROXY-3-(3-PHENOXY)PHENYL-2(1H)-QUINOLINONE
7-chloro-4-hydroxy-3-(3-phenoxyphenyl)-1H-quinolin-2-one
7-CHLORO-4-HYDROXY-3-(3-PHENOXY )PHENYLQUINOLIN-2[1H]-ONE
2(1H)-Quinolinone, 7-chloro-4-hydroxy-3-(3-phenoxyphenyl)- | [Molecular Formula]
C21H14ClNO3 | [MDL Number]
MFCD00910917 | [MOL File]
142326-59-8.mol | [Molecular Weight]
363.79 |
| Chemical Properties | Back Directory | [Melting point ]
308 °C | [Boiling point ]
584.7±50.0 °C(Predicted) | [density ]
1.389±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
DMSO: soluble36.4mg/mL | [form ]
solid | [pka]
4.50±1.00(Predicted) |
| Hazard Information | Back Directory | [Uses]
L-701,324 is a potential anticonvulsant with high selectivity and affinity for the NMDA receptor glycine site. NMDA receptors are expressed by small-cell lung cancer and are potential targets for effective treatment. | [Definition]
ChEBI: 7-chloro-4-hydroxy-3-(3-phenoxyphenyl)-1H-quinolin-2-one is a member of quinolines. | [Biological Activity]
An orally active and long acting anticonvulsant with high affinity and selectivity for the glycine site on the NMDA receptor. | [storage]
Store at RT |
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