| Identification | Back Directory | [Name]
(2R,3R)-3,5,7-Trihydroxy-2-[(2S,3S)-2-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-2,3-dihydrobenzo[1,4]dioxin-6-yl]-4-chromanone | [CAS]
142796-22-3 | [Synonyms]
Isosilybin B
Isosilybin B，ISB-B
Isosilybin B/(-)-Isosilybin B,Silybin a2
(2R,3R)-3,5,7-Trihydroxy-2-[(2S,3S)-2-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-2,3-dihydrobenzo[1,4]dioxin-6-yl]-4-chromanone
4H-1-Benzopyran-4-one, 2-[(2S,3S)-2,3-dihydro-2-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-1,4-benzodioxin-6-yl]-2,3-dihydro-3,5,7-trihydroxy-, (2R,3R)- | [Molecular Formula]
C25H22O10 | [MDL Number]
MFCD18783097 | [MOL File]
142796-22-3.mol | [Molecular Weight]
482.44 |
| Chemical Properties | Back Directory | [Melting point ]
194-196 °C(Solv: methanol (67-56-1)) | [Boiling point ]
793.0±60.0 °C(Predicted) | [density ]
1.527±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
Soluble in DMSO | [form ]
neat | [pka]
7.39±0.60(Predicted) | [color ]
White to off-white | [InChIKey]
FDQAOULAVFHKBX-WAABAYLZSA-N | [SMILES]
[C@H]1(C2=CC=C3O[C@@H](C4=CC=C(O)C(OC)=C4)[C@H](CO)OC3=C2)OC2=CC(O)=CC(O)=C2C(=O)[C@@H]1O |
| Hazard Information | Back Directory | [Uses]
Isosilybin B is one of the flavonolignans extracted from the seeds of milk thistle. Isosilybin B was the most consistently potent suppressor of cell growth. Isosilybin A (I901002) and isosilybin B were also the most effective suppressors of prostate-?specific antigen secretion by androgen-?dependent LNCaP cells. | [storage]
Store at -20°C |
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