143692-48-2

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143692-48-2 Structure

Identification	Back Directory
[Name] 1-(4-Aminophenyl)-3-methylcarbamyl-4-methyl-3,4-dihydro-7,8-methylenedioxy-5H-2,3-benzodiazepinehydrochloride
[CAS] 143692-48-2
[Synonyms] GYKI-53655 hydrate GYKI 53655 hydrochloride LY300168 hydrochloride hydrate 1-(4-Aminophenyl)-3-methylcarbamyl-4-methyl-3,4-dihydro-7,8-methylenedioxy-5H-2,3-benzodiazepinehydrochloride 5-(4-Aminophenyl)-8,9-dihydro-N,8-dimethyl-7H-1,3-dioxolo[4,5-h][2,3]benzodiazepine-7-carboxamide hydrochloride
[Molecular Formula] C19H21ClN4O3
[MDL Number] MFCD01941362
[MOL File] 143692-48-2.mol
[Molecular Weight] 388.848

Safety Data	Back Directory
[Symbol(GHS) ] GHS06
[Signal word ] Danger
[Hazard statements ] H301
[Precautionary statements ] P301+P310
[Hazard Codes ] T
[Risk Statements ] 25
[Safety Statements ] 45
[RIDADR ] UN 2811 6.1 / PGIII
[WGK Germany ] 1

Hazard Information	Back Directory
[Uses] GYKI 53655 Hydrochloride is a non-competitive AMPA antagonist,.
[Biological Activity] GYKI-53655 also inhibits the kainate GluK3 homomeric and GluK2/3 heteromeric receptors. It exhibits anti-ischemicanti-convulsantand acute neuroprotective activity.''GYKI-53655 is an AMPA antagonist and noncompetitive negative allosteric modulator.
[storage] Desiccate at RT

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