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144231-85-6

144231-85-6 Structure

144231-85-6 Structure
IdentificationBack Directory
[Name]

CarbaMic acid, [(1S)-1-[[[(1S)-3-[[(3,5-diMethoxyphenyl)Methyl]aMino]-1-ethyl-2,3-dioxopropyl]aMino]carbonyl]-3-Methylbutyl]-, phenylMethyl ester (9CI)
[CAS]

144231-85-6
[Synonyms]

Calpain-2-IN-1
benzyl ((S)-1-(((S)-1-((3,5-dimethoxybenzyl)amino)-1,2-dioxopentan-3-yl)amino)-4-methyl-1-oxopentan-2-yl)carbamate
CarbaMic acid, [(1S)-1-[[[(1S)-3-[[(3,5-diMethoxyphenyl)Methyl]aMino]-1-ethyl-2,3-dioxopropyl]aMino]carbonyl]-3-Methylbutyl]-, phenylMethyl ester (9CI)
[Molecular Formula]

C28H37N3O7
[MDL Number]

MFCD28400876
[MOL File]

144231-85-6.mol
[Molecular Weight]

527.61
Chemical PropertiesBack Directory
[density ]

1.168±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[form ]

Solid
[pka]

11.10±0.46(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

Calpain-2-IN-1 (Formula 1A) is a isoform-specific calpain-2 inhibitor with Kis of 181 nM and 7.8 nM for calpain-1, and calpain-2, respectively.?Calpain-2-IN-1 can be used for the research of neurodegenerative diseases and other diseases of synaptic function[1].
[storage]

Store at -20°C
[References]

[1] Michel Baudry, et al. Isoform-specific calpain inhibitors, methods of identification, and uses thereof. WO2016077461A2.
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