| Identification | Back Directory | [Name]
SEMBL | [CAS]
1443448-82-5 | [Synonyms]
SEMBL
2-hydroxy-N-[(3S)-4-methylene-5-oxo-tetrahydrofuran-3-yl]benzamide
Benzamide, 2-hydroxy-N-[(3S)-tetrahydro-4-methylene-5-oxo-3-furanyl]-
SEMBL (S)-beta-Salicyloylamino-alpha-exo-methylene-gamma-
butyrolactone | [Molecular Formula]
C12H11NO4 | [MDL Number]
MFCD31925192 | [MOL File]
1443448-82-5.mol | [Molecular Weight]
233.22 |
| Chemical Properties | Back Directory | [Boiling point ]
536.7±50.0 °C(Predicted) | [density ]
1.36±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [form ]
Solid | [pka]
8.29±0.30(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
SEMBL is a potent NF-κB inhibitor. SEMBL can inhibit NF-κB-DNA binding, and also inhibits NF-κB-dependent inflammatory cytokine secretions. SEMBL inhibits cancer cell migration and invasion via decreasing MMP expression. SEMBL can be used for researching anticancer[1]. | [References]
[1] Umezawa K, et al. Inhibition of matrix metalloproteinase expression and cellular invasion by NF-κB inhibitors of microbial origin. Biochim Biophys Acta Proteins Proteom. 2020;1868(6):140412. DOI:10.1016/j.bbapap.2020.140412 |
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| Company Name: |
cjbscvictory
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| Tel: |
13348960310 |
| Website: |
https://www.weikeqi-biotech.com/ |
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